Evidence map›Paper›PMID 40421445›Full record

ArticleBJA open2025

Preoperative submaximal cardiopulmonary exercise testing and its association with early postoperative complications.

Zyad J Carr, Jean Charchaflieh, Andres Brenes-Bastos, Hugo He, Hung-Mo Lin, Amanda Jankelovits, Emily Gu, Jill Zafar, Fed Ghali, Wei S Tan and 1 more

2 registry-linked trialsAbstract read
In one paragraph

Article in BJA open, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to 2 registered trials, which are not on this map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

NCT05743673 recruitingnot on this map

A Feasibility Study of the SHAPE™ Test of Aerobic Fitness in Older Adults Presenting for Moderate to High-risk Surgery

TypeobservationalSponsorYale UniversityRan2023 to 2026Enrolled371ConditionsPerioperative/Postoperative Complications, Aerobic CapacityArmsShape II
NCT07519733 recruitingnot on this map

Submaximal Cardiopulmonary Exercise Testing in Adults Presenting for Moderate to High-risk Surgery and Perioperative Outcomes

Typeobservational_patient_registrySponsorYale UniversityRan2025 to 2028Enrolled992ConditionsPostoperative Complications (Cardiopulmonary)ArmsRecruited participants receive preoperative rapid submaximal cardiopulmonary exercise testing within the current risk assessment framework of the pre-surgical evaluation clinic
3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Zyad J CarrYale University, School of Medicine, New Haven, CT, USA.
Jean CharchafliehYale University, School of Medicine, New Haven, CT, USA.
Andres Brenes-BastosYale University, School of Medicine, New Haven, CT, USA.
Hugo HeYale Center for Analytical Sciences, New Haven, CT, USA.
Hung-Mo LinDepartment of Anesthesiology, Yale New Haven Hospital, New Haven, CT, USA.
Amanda JankelovitsYale University, School of Medicine, New Haven, CT, USA.
Emily GuYale University, School of Medicine, New Haven, CT, USA.
Jill ZafarYale University, School of Medicine, New Haven, CT, USA.
Fed GhaliYale University, School of Medicine, New Haven, CT, USA.
Wei S TanYale University, School of Medicine, New Haven, CT, USA.
Paul HeerdtYale University, School of Medicine, New Haven, CT, USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background: Early postoperative complication risk prediction would enhance perioperative surveillance and resource allocation. Reports have described brief submaximal cardiopulmonary exercise testing (CPET) for the routine assessment of cardiopulmonary disease. Compared with conventional CPET, it can be performed in 6 min and is used to predict peak CPET measurements. We aimed to determine whether submaximal CPET-derived measures outperform structured surveys in early postoperative complication detection. Methods: An institutional review board-approved, single-centre, open-label, clinical device trial was conducted. A total of 101 participants undergoing noncardiac surgery, aged >60 yr, with revised cardiac risk index ≤2, self-reported metabolic equivalents >4 (METs in ml O Results: Of 101 participants, 53 (52.4%) had POMS ≥1. GXCAP to peak VO Conclusions: Compared with structured surveys (subjective METs or Duke Activity Status Index) or conventional peak CPET values (VO Clinical trial registration: NCT05743673.

Indexed as

early postoperative complicationspreoperative evaluationpreoperative functional capacitypreoperative risk stratificationsubmaximal cardiopulmonary exercise testing

Identifiers

PMID40421445
PMCPMC12105740

What OpenQuestion holds

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Registered trials

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.