ArticleFood science & nutrition2025
Comparative Study on the Prokinetic Effects of Ginger, Caraway, and Peppermint in Relieving Gastrointestinal Disturbances in Pulmonary TB Patients: A Clinical Trial.
Article in Food science & nutrition, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. It is linked to trial NCT06157034 (Prokinetic Effect of Selected Nutraceuticals on Management of Gastrointestinal Disturbances Among Pulmonary Tuberculosis Patients), which is not on this map. Cited by 1 paper.
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Prokinetic Effect of Selected Nutraceuticals on Management of Gastrointestinal Disturbances Among Pulmonary Tuberculosis Patients
Who cites it
1 citing paper in PubMed.
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Authors and funding
3 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Anti-tuberculosis treatment (ATT) leads to adverse gastrointestinal disturbances (vomiting, nausea, postprandial distress) due to its prolonged duration in TB patients. This study assessed the prokinetic effects of ginger, caraway, and peppermint nutraceuticals in alleviating these symptoms in pulmonary TB patients on ATT. The selected nutraceuticals were procured, cleaned, dried, and crushed to perform proximate analysis, TPC, TFC, DPPH, ABTS, and FRAP. Further, a randomized clinical trial (Registered No. NCT06157034) involved 200 participants divided into four groups (placebo = 48, ginger = 47, caraway = 48, peppermint = 46), with 11 dropouts. Participants received varied dosages of selected nutraceuticals (Ginger: 1 g, Caraway: 2 g, and Peppermint: 3 mL daily), and data were collected at baseline, intervention (after 3 months), and washout (after 1 month) phases. Ginger and peppermint showed the highest moisture content (81.67%, 81.74%), while caraway had the highest protein (29.72%) and crude fiber (45.11%). Peppermint had the highest crude fat (54.47%) and crude fiber (4.81%). Moreover, ginger had the highest TPC (1035.51 mgGAE/g) and TFC (465.34 mgQE/g), with notable DPPH, FRAP, and ABTS values. Participants had a mean age (39.03 years), family income (17,385 ± 528.72Rs), and BMI (19.43 ± 5.67). Sputum testing and other biochemical analyses were also done. Energy and macronutrient consumption did not differ significantly across all phases (
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