Evidence map›Paper›PMID 40421397›Full record

ReviewInternational journal of hematology-oncology and stem cell research2025

Cardiac Considerations in Hematopoietic Stem Cell Transplantation (HSCT) for Transfusion-Dependent Thalassemia: A Review.

Saeed Nateghi, Aziz Rasooli, Leila Moaddabshoar, Zahra Panahi, Mohammad Reza Rostami

Abstract readReview
PubMed Full text at PMC Publisher
In one paragraph

Review in International journal of hematology-oncology and stem cell research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Observational
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

5 authors.

Saeed NateghiDepartment of Cardiology, Baharloo Hospital, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Aziz RasooliDepartment of Emergency Medicine, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Leila MoaddabshoarHead of Prevention and Cancer Control Group, Ministry of Health and Medical Education, Tehran, Iran.
Zahra PanahiDepartment of Perinatology, School of Medicine, Tehran University of Medical Sciences, Tehran, Iran.
Mohammad Reza RostamiResearch Institute for Oncology, Hematology and Cell Therapy, Tehran University of Medical Sciences, Tehran, Iran.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Hematopoietic stem cell transplantation (HSCT) is a potentially curative treatment option for several malignant and non-malignant hematologic disorders, including transfusion-dependent thalassemia (TDT). However, HSCT is associated with short-term and long-term complications. One of the recognized causes of morbidity and mortality in TDT patients is heart-related complications. Additionally, cardiac involvement is likely to be more common in patients proceeding to HSCT. Thus, the risks of cardiac complications should be carefully weighed against the benefits of the primary disease cure. This review attempted to discuss the cardiac considerations in TDT patients undergoing HSCT

Indexed as

CardiomyopathyCardiotoxicityGraft-versus-host diseaseHematopoietic stem cell transplantTransfusion-dependent thalassemia

Identifiers

PMID40421397
PMCPMC12103821

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.