Evidence map›Paper›PMID 40421381›Full record

ReviewEuropean heart journal. Imaging methods and practice2025

Contemporary review of the clinical features, multi-modality imaging, and management of coronary artery aneurysms.

Sharmeen Sorathia, Aro Daniela Arockiam, Ankit Agrawal, Elio Haroun, Rishabh Khurana, Abdelrahman Ahmed, Leslie Cho, Wael Jaber, Brian Griffin, Tom Kai Ming Wang

Abstract readReview
In one paragraph

Review in European heart journal. Imaging methods and practice, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 7 papers.

0numbers the graph read from it
0cells of the map it votes in
7citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

7 citing papers in PubMed.

  1. Article
  2. Review
  3. Article
  4. When giant coronary aneurysms masquerade as cardiac masses.European heart journal. Case reports · 2026
    Article
  5. Article
  6. The Pathophysiology of Coronary Artery Disease.The International journal of angiology : official publication of the International College of Angiology, Inc · 2025
    Review
  7. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Sharmeen SorathiaDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.ORCID https://orcid.org/0009-0004-2109-7806
Aro Daniela ArockiamDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.
Ankit AgrawalDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.
Elio HarounDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.
Rishabh KhuranaDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.
Abdelrahman AhmedDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.
Leslie ChoDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.ORCID https://orcid.org/0000-0002-1190-1774
Wael JaberDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.ORCID https://orcid.org/0000-0001-5642-2112
Brian GriffinDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.
Tom Kai Ming WangDepartment of Cardiovascular Medicine, Heart, Vascular and Thoracic Institute, Cleveland Clinic, 9500 Euclid Avenue, Desk J1-5, Cleveland, OH 44195, USA.ORCID https://orcid.org/0000-0001-5570-9402

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Coronary artery aneurysm (CAA) is a rare, dilated segment of the coronary artery. Phenotypically, it can have different morphologies, patterns, content, and affected vessels, making multimodality invasive and noninvasive imaging play a significant role in its evaluation. In this review article, we discuss in depth the contemporary perspectives in pathophysiology, epidemiology, clinical presentation, multimodality imaging evaluation, treatment strategies (medical, percutaneous and surgical) and outcomes of CAA. CAA is predominantly associated with coronary atherosclerotic diseases and/or autoimmune vasculitis conditions including Kawasaki disease. It can present with various clinical manifestations, from an incidental finding to myocardial infarction and life-threatening complications. While coronary angiography has been the gold standard to detect CAA, noninvasive modalities including coronary computed tomography have increasingly been utilized given its high resolution for anatomical depiction of the vessels and relations to surrounding structures. We suggest a stepwise approach to the assessment and clinical decision-making in the management of CAA. Pharmacological strategies include risk factor control and secondary prevention. For obstructive ischaemic presenting aneurysms, percutaneous is pursued, while larger or multi-vessel obstructive lesions are typically managed with coronary surgery.

Indexed as

atherosclerosiscardiac magnetic resonance imagingcoronary angiographycoronary artery aneurysmcoronary computed tomographymultimodality imaging

Identifiers

PMID40421381
PMCPMC12103974

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.