Evidence map›Paper›PMID 40421376›Full record

ArticleAI and ethics2025

Tempered enthusiasm by interviewed experts for synthetic data and ELSI checklists for AI in medicine.

Laura Y Cabrera, Jennifer Wagner, Sara Gerke, Daniel Susser

Abstract read
In one paragraph

Article in AI and ethics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Laura Y Cabrera *Department of Engineering Science and Mechanics, Pennsylvania State University, W-316 Millennium Science Complex, University Park, PA 16802 USA.ORCID 0000-0002-6220-7096
Jennifer Wagner *Huck Institutes of the Life Sciences, Pennsylvania State University, University Park, PA 16802 USA.ORCID 0000-0002-2278-0306
Sara GerkeCollege of Law and European Union Center, University of Illinois Urbana-Champaign, Champaign, IL 61820 USA.ORCID 0000-0002-5718-3982
Daniel SusserDepartment of Information Science, Cornell University, Ithaca, NY 14853 USA.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Synthetic data are increasingly being used in data-driven fields. While synthetic data is a promising tool in medicine, it raises new ethical, legal, and social implications (ELSI) challenges. There is a recognized need for well-designed approaches and standards for documenting and communicating relevant information about artificial intelligence (AI) research datasets and models, including consideration of the many ELSI challenges. This study investigates the ethical dimensions of synthetic data and explores the utility and challenges of ELSI-focused computational checklists for biomedical AI via semi-structure interviews with subject matter experts. Our results suggest that AI experts have tempered views about the promises and challenges of both synthetic data and ELSI-focused computational checklists. Experts discussed a number of ELSI issues covered by previous literature on the topic, such as issues of bias and privacy, yet other less discussed ELSI issues, such as social justice implications and issues of trust were also raised. When discussing ELSI-focused computational checklists our participants highlighted the challenges connected to developing and implementing them. Supplementary Information: The online version contains supplementary material available at 10.1007/s43681-024-00652-x.

Indexed as

Artificial intelligenceComputational checklistsELSISynthetic data

Identifiers

PMID40421376
PMCPMC12103352

What OpenQuestion holds

Textmetadata
LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.