Evidence map›Paper›PMID 40421358›Full record

ArticleFrontiers in public health2025

Risk of mental health conditions in bereavement: a population-based analysis of lung cancer spouses.

Djin L Tay, Kline Dubose, Jonathan Chipman, Lee Ellington, Malek Alnajar, Eli Iacob, Caroline Stephens, Katherine A Ornstein

Abstract read
In one paragraph

Article in Frontiers in public health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

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2 · The registry

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. Review
4 · The record

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5 · Who and what money

Authors and funding

8 authors.

Djin L TayCollege of Nursing, University of Utah, Salt Lake City, UT, United States.
Kline DuboseDepartment of Population Health Sciences, School of Medicine, University of Utah, Salt Lake City, UT, United States.
Jonathan ChipmanDepartment of Population Health Sciences, School of Medicine, University of Utah, Salt Lake City, UT, United States.
Lee EllingtonCollege of Nursing, University of Utah, Salt Lake City, UT, United States.
Malek AlnajarCollege of Nursing, University of Utah, Salt Lake City, UT, United States.
Eli IacobCollege of Nursing, University of Utah, Salt Lake City, UT, United States.
Caroline StephensCollege of Nursing, University of Utah, Salt Lake City, UT, United States.
Katherine A OrnsteinSchool of Nursing, Johns Hopkins University, Baltimore, MD, United States.

Funding

UTAH REGIONAL CANCER CENTERP30CA042014 · NCI · UTAH STATE HIGHER EDUCATION SYSTEM--UNIVERSITY OF UTAH · PI Jared P Rutter · 1986 to 2026
$72.6M
Research Collaborative for Family Caregivers of Older AdultsK07AG068185 · NIA · UNIVERSITY OF UTAH · PI ELLINGTON, LEE A · 2020 to 2024
$810k
Sharing statewide health data for genetic research (1 R01 RR021746-01A1)R01RR021746 · NCRR · UNIVERSITY OF UTAH · PI MINEAU, GERALDINE P · 2007 to 2009
$770k
From genomics to natural language processing: A protected environment for research computing in the health scienceS10OD021644 · OD · UNIVERSITY OF UTAH · PI CHEATHAM, THOMAS E. · 2017 to 2017
$494k
NCI NIH HHS HHSN261201800016CNCI NIH HHS HHSN261201800016INCI NIH HHS P30 CA042014NCRR NIH HHS R01 RR021746NIA NIH HHS K07 AG068185NIH HHS S10 OD021644
6 · The paper itself

Abstract

Background: Caregiving to lung cancer patients is distressing, isolating, and associated with a high burden of anxiety and depression. However, few population-based studies in the U.S. have examined the risk of mental health conditions (MHCs) among spouses of lung cancer patients after the death of their partner. Guided by Anderson's Behavioral Health Utilization model, we examined the role of sex, pre-bereavement MHC, and decedents' healthcare utilization on the risk of having a diagnosed MHC after the death of a lung cancer patient. Methods: This retrospective cohort study linked state-wide health facility records of 1,224 dyads-deceased lung cancer patients and their bereaved spouses (824 female, 400 male)-in Utah between 2013 and 2021. Bereavement-related mood/stress-related conditions were identified for spouses using diagnostic codes (starting from day 1 following the patients' deaths). The Kaplan-Meier curves and Cox proportional hazard models were used to estimate the risk for a composite outcome of MHC/death and the risk of MHC, after adjusting for censorship due to death and controlling for covariates. Results: The majority of spouses were aged 65+ (female: 67%; male: 33%), white/non-Hispanic (female: 89%; male: 90%), and urban-dwelling (female: 69%; male: 71%). Spouses experienced 374 events (MHCs/death) across the follow-up period. Adjusting for census-tract level income, cancer stage, insurance, censoring due to death, and the interaction between sex and MHC, spouses with preexisting MHCs had 4.09 times higher risk of developing MHCs during bereavement (95% CI: 2.70, 6.19) compared to spouses without pre-existing MHCs. Spouses of decedents with some college education (aHR: 0.68, 95% CI = 0.48-0.97) and longer survival (aHR: 0.85, 95% CI = 0.74-0.99) had a lower risk of MHCs compared to those of decedents with high school education and shorter survival. Discussion: This population-based study supports evidence for multi-level risk factors associated with having MHC after the death of a spouse with lung cancer. Findings suggest the need for targeted bereavement support for subgroups of spouses at greater risk of MHCs.

Indexed as

BereavementLung NeoplasmsMental DisordersSpousesAdultAgedFemaleHumansMaleMiddle AgedRetrospective StudiesRisk FactorsUtahbereavementcaregiver stressepidemiologic studiesmental healthneoplasms

Identifiers

PMID40421358
PMCPMC12104072

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.