Evidence map›Paper›PMID 40421351›Full record

ArticleCureus2025

Acute Deep Vein Thrombosis Presents as an Early Complication of Wilson Disease.

Aseel Faroun, Roua Faroun, Rania Mashal, Mutaz Sultan

Abstract readCase Reports
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

4 authors.

Aseel FarounMedicine, Al-Quds University, Jerusalem, PSE.
Roua FarounMedicine, Al-Quds University, Jerusalem, PSE.
Rania MashalMedicine, Al-Quds University, Jerusalem, PSE.
Mutaz SultanPediatric Gastroenterology, Al-Makassed Hospital, Al-Quds University, Jerusalem, PSE.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Wilson disease (WD) is a rare, autosomal recessive disorder of copper metabolism. Although hepatic and neuropsychiatric manifestations are common, thrombotic events such as deep vein thrombosis (DVT) are exceedingly rare, particularly in pediatric patients. We present the case of an 11-year-old girl diagnosed with WD who developed an acute left upper limb DVT shortly two months after diagnosis. Laboratory and imaging findings confirmed hepatic involvement and coagulopathy. Genetic testing revealed a heterozygous Factor V Leiden mutation and MTHFR heterozygosity; both may have contributed to the thrombotic episode. Careful monitoring of WD was prioritized, and appropriate treatment plans were established during diagnosis to achieve satisfactory outcomes and prevent future thrombotic sequences. This case emphasizes the importance of early recognition of thrombotic complications and coagulopathy management in pediatric WD.

Indexed as

deep vein thrombosishepatic coagulopathypediatric thrombosisrare presentationwilson disease

Identifiers

PMID40421351
PMCPMC12105762

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.