Evidence map›Paper›PMID 40421344›Full record

ArticleCureus2025

Association of Anaemia With Higher Mortality and Disability After Subarachnoid Haemorrhage: A Single-Centre Cohort Study.

Priyavarshini Ramesh, Mark Horner, Marcus Abbawy, Finlay Holden, Suresh Renukappa, Subashini Suresh, Cyril Chacko, Randeep Mullhi, Sree Chaitanua Rudrapatma Sathyamurthy, Tonny Veenith

Abstract read
In one paragraph

Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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0citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

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Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Priyavarshini RameshDepartment of Critical Care Medicine, Guy's and St Thomas' NHS Foundation Trust, London, GBR.
Mark HornerDepartment of Anaesthesia, University Hospitals Birmingham NHS Foundation Trust, Birmingham, GBR.
Marcus AbbawyDepartment of Critical Care and Acute Care Medicine, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.
Finlay HoldenDepartment of Critical Care and Acute Care Medicine, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.
Suresh RenukappaDepartment of Critical Care and Acute Care Medicine, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.
Subashini SureshFaculty of Science and Engineering, University of Wolverhampton, Wolverhampton, GBR.
Cyril ChackoDepartment of Critical Care and Acute Care Medicine, The Royal Wolverhampton NHS Trust, Wolverhampton, GBR.
Randeep MullhiDepartment of Anaesthesia, University Hospitals Birmingham NHS Foundation Trust, Birmingham, GBR.
Sree Chaitanua Rudrapatma SathyamurthyDepartment of Critical Care Medicine, Dr B.R. Ambedkar Medical College and Hospital, Bengaluru, IND.
Tonny VeenithFaculty of Science and Engineering, University of Wolverhampton, Wolverhampton, GBR.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundCritical care management in subarachnoid haemorrhage (SAH) aims to facilitate neuroprotection and prevent secondary neurological insults. Anaemia after SAH leads to reduced cerebral oxygen delivery and poor outcomes. This study aimed to investigate the association between anaemia and mortality and morbidity outcomes in patients with SAH in tertiary centres, as well as evaluate the impact of blood transfusions on outcomes in anaemic SAH patients.  Methods: We performed a retrospective study of 987 patients with SAH at a tertiary neurocritical care centre between September 2016 and September 2018. Data were collected on baseline characteristics, World Federation of Neurosurgical Societies SAH grade, secondary insults such as anaemia and hydrocephalus, and units of blood transfused. The primary outcome was to investigate the correlation between anaemia and 28-day Modified Rankin Scale (MRS) score. Secondary outcomes were delayed neurological deficits, length of stay and death in the intensive care unit (ICU). Anaemia was defined as haemoglobin (Hb) ≤ 95 g/L, and severe anaemia as Hb≤80 g/L.  Results: Of the patients, 28.7% had anaemia and 12% had severe anaemia. Anaemia after SAH was associated with an increased risk of death or severe disability (p<0.001), worse survival outcomes (p<0.001) and increased length of stay in ICU (p<0.001).

conclusionsAnaemia after SAH is associated with a significant increase in mortality and morbidity and should be monitored closely and corrected.

Indexed as

acute subarachnoid haemorrhageanaemiablood transfusionintracerebral aneurysmsneurointensive care unit

Identifiers

PMID40421344
PMCPMC12105551

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