ArticleCureus2025
Hairy Cell Leukemia and Its Mimics: A Case-Based Exploration of Diagnostic Complexity.
Article in Cureus, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
13 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
Hairy cell leukemia (HCL) is a rare but well-characterized B-cell malignancy with distinct immunophenotypic and genetic features. Advances in molecular diagnostics, particularly the identification of the BRAF V600E mutation, have significantly enhanced diagnostic precision and informed targeted treatment strategies. However, the HCL variant and other HCL-like syndromes continue to present substantial diagnostic challenges due to their absence of BRAF mutations, atypical immunophenotypic profiles, and divergent clinical courses. This case report provides an overview of the morphological, immunophenotypic, molecular, and histopathological features of HCL, as well as its differential diagnoses, with a focus on the utility of flow cytometry and emerging molecular diagnostic markers. To underscore the practical implications of these diagnostic complexities, we present a case report that reinforces the challenges in distinguishing HCL from its mimics and highlights the role of contemporary integrated diagnostic methodologies.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.