Evidence map›Paper›PMID 40421253›Full record

ArticleHealth science reports2025

Osteoarticular Complications of Sickle Cell Disease in Bukavu: A Retrospective Multicenter Cross-Sectional Study.

Rodrigue Mwenibamba Mupenda, Alexandre Nechi Nakashenyi, Daniel Safari Nteranya, Viviane Feza Bianga Viviane, Fernand Manga Opondjo, Sarah Mbula Mulasi, Didier Mbilizi Kasilembo, Christian Bisimwa Wabene, Eugene Munyantwari Akomu, Uwonda Akinja and 1 more

Abstract read
In one paragraph

Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Rodrigue Mwenibamba MupendaCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.
Alexandre Nechi NakashenyiCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.
Daniel Safari NteranyaCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.ORCID https://orcid.org/0000-0001-5170-7442
Viviane Feza Bianga VivianeCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.
Fernand Manga OpondjoCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.
Sarah Mbula MulasiCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.
Didier Mbilizi KasilemboCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.
Christian Bisimwa WabeneCliniques Universitaires de Bukavu, Faculty of Medicine Université Officielle de Bukavu Bukavu Democratic Republic of Congo.ORCID https://orcid.org/0000-0003-3861-6401
Eugene Munyantwari AkomuFaculty of Medicine University of Goma Goma Democratic Republic of Congo.
Uwonda AkinjaFaculty of Medicine University of Mbuji Mayi Mbuji Mayi Democratic Republic of Congo.
Jean Marrie Vianney Tshimbila KabanguFaculty of Medicine University of Kisangani Kisangani Democratic Republic of Congo.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Background and Aim: This study aimed to investigate the epidemiological, clinical, and therapeutic aspects of osteoarticular complications in patients with sickle cell disease in Bukavu. Methods: We conducted a multicenter cross-sectional study over 5 years, focusing on 31 patients with sickle cell disease who were admitted for osteoarticular complications in Bukavu. Data were collected from medical records and analyzed with the Statistical Package for Social Science 26 (IBM, SPSS 26). Results: We recorded 31 (6.07%) sickle cell patients with osteoarticular complications, with a mean age of 10.5 ± 5.6 years (extremes: 2-30 years). Pain, fever, and functional impotence were the most frequent reasons for consultation with 9 (29.03%) patients. Septic arthritis was the most common complication in 10 (32.26%), followed by osteonecrosis of the femoral head in 8 (25.81%), chronic osteomyelitis in 7 (22.58%) cases, and acute osteomyelitis in 4 (12.70%) patients. The femur was the most affected bone. Articular complications predominantly impacted larger joints, with the knee joint experiencing the highest rate of damage, occurring in 38.71% of cases. Treatment, including medical and surgical methods, was provided in 16 cases (51.6%). Complete healing without residual effects was achieved in 22 patients (70.96%). Conclusion: The osteoarticular complications of sickle cell disease are frequent in the city of Bukavu, and regular monitoring and early consultation would enable early diagnosis and management.

Indexed as

femoral head necrosisosteomyelitisseptic arthritissickle cell disease

Identifiers

PMID40421253
PMCPMC12104867

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.