ArticleHealth science reports2025
The Impact of Malnutrition on Perioperative Ischemic Stroke in Transcatheter Aortic Valve Replacement (TAVR): A Retrospective Cohort Study of the National Inpatient Sample.
Article in Health science reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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10 authors.
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Abstract
Background and Aims: Ischemic stroke is a serious risk for patients undergoing transcatheter aortic valve replacement (TAVR). The relationship between malnutrition and post-TAVR ischemic stroke remains unclear. This study investigates this association using the National Inpatient Sample (NIS) data. Methods: A retrospective observational study was conducted using NIS data from 2012 to 2021. We included patients who underwent TAVR and were diagnosed with malnutrition based on ICD-9 and ICD-10 codes. Patients under 18 years, with a history of preoperative stroke, with both ischemic and hemorrhagic strokes, or with incomplete data were excluded. Logistic regression was performed to evaluate the association between malnutrition and ischemic stroke, adjusting for potential confounders. Sensitivity analyses included stratified analysis and propensity score matching. Results: Among 364,580 TAVR patients, 10,415 (2.86%) were diagnosed with malnutrition. Malnourished patients were older (78.04 vs. 77.40), predominantly white (85.69%), and had a higher incidence of ischemic stroke (11.47% vs. 7.25%, Conclusion: Malnutrition is associated with a higher risk of ischemic stroke following TAVR, highlighting the need for targeted interventions.
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