ArticleFrontiers in endocrinology2025
Evaluating indices of insulin resistance and estimating the prevalence of insulin resistance in a large biobank cohort.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers.
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Who cites it
23 citing papers in PubMed.
- Association of Serum Lithium Levels with Insulin Resistance in Type-2 Diabetes Patients.Biological trace element research · 2026Article
- Review
- Effects of High-Intensity Interval Training and Moderate-Intensity Continuous Training on Insulin Resistance Markers in Overweight and Obese Moroccan Adolescents.Sports (Basel, Switzerland) · 2026Article
- Firmicutes/Bacteroidetes ratio of the gut microbiota and its association with abdominal obesity and insulin resistance (METS-IR) in Korean adults.Scientific reports · 2026Article
- Evaluation of body mass index, waist-to-hip ratio, and waist-to-height ratio as predictors of insulin resistance in Syrian adult women: A cross-sectional study.The Journal of international medical research · 2026Article
- CELF family of RNA-binding proteins: roles in disease biology and potential for therapeutic intervention.Cell communication and signaling : CCS · 2026Review
- A practical tool for risk stratification: eGDR as a predictor of incident diabetic kidney disease.BMC endocrine disorders · 2026Article
- Ectopic fat distribution and its correlation with insulin resistance indices in non-obese individuals with type 2 diabetes.Acta diabetologica · 2026Article
- Insulin Resistance and Inflammation.International journal of molecular sciences · 2026Review
- The transition from preclinical to clinical obesity: the importance of a borderline stage.Clinical science (London, England : 1979) · 2026Review
- The insulin resistance-systemic vascular resistance-isolated diastolic hypertension axis: a metabolic framework for an overlooked hypertension phenotype.Frontiers in cardiovascular medicine · 2026Review
- From Engel's Bio-Psycho-Social model to the personalized health determinants model: a comprehensive framework and illustrative operationalization for precision health.Frontiers in digital health · 2026Article
- Cholesterol, high-density lipoprotein, and glucose (CHG) index and incident impaired fasting glucose in Chinese adults: a retrospective longitudinal cohort study.Frontiers in nutrition · 2026Article
- Discriminating prevalent type 2 diabetes among community-dwelling older adults with metabolic dysfunction-associated steatotic liver disease: a comparative analysis of 12 insulin resistance surrogates.Frontiers in endocrinology · 2026Article
- Cross-lag association between TyG-CVAI and frailty index: evidence from a natural population cohort in southwestern China.Frontiers in public health · 2026Article
- Association between the composite dietary antioxidant index and chronic rhinosinusitis burden: the potential mediating role of insulin resistance.Frontiers in nutrition · 2026Article
- Insulin resistance in cerebral small vessel disease: a mini review.Frontiers in neuroscience · 2026Review
- Assessment of triglyceride glucose index and triglyceride to HDL cholesterol ratio as markers of insulin resistance defined by the Homeostatic Model Assessment 2 in Middle Eastern adults with excess adiposity.Medicine and pharmacy reports · 2026Article
- N-lactoyl amino acids are potential biomarkers for insulin resistance and diabetic complications.Diabetes, obesity & metabolism · 2025Article
- The Triglyceride-Glucose Index: A Clinical Tool to Quantify Insulin Resistance as a Metabolic Myocardial Remodeling Bridge in Atrial Fibrillation.Biomedicines · 2025Review
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6 authors.
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Abstract
Introduction: Insulin resistance (IR) is involved in the pathogenesis of various metabolic disorders. Several surrogate indices of IR have been proposed. We assessed the performance of seven clinically relevant indirect measures of IR and estimated the prevalence of IR in a large population-based cohort. Methods: The study was conducted on fasting individuals from the Qatar biobank (QBB) participants ( Results: The cut-off for HOMA-IR was determined at 1.878, HOMA2-IR (insulin); 1.128, HOMA2-IR (C-peptide); 1.307, QUICKI; 0.347, TyG; 8.281, McAi; 7.727 and 1.718 for TG/HDL. All IR indices analyzed yielded AUC values ranging from 0.83 to 0.92. TyG was the most robust measure for IR (AUC = 0.92, Sensitivity = 0.90, Specificity = 0.79). The overall prevalence of IR in Qatar was estimated at ~51 - 65%. Conclusions: TyG index was the most robust index for determining IR in the Qatari population. The proposed cut-offs could serve as a reference in Middle Eastern populations for IR screening.
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