ArticleFrontiers in endocrinology2025
Insulin resistance assessed by estimated glucose disposal rate and the risk of abdominal aortic calcification: findings from a nationwide cohort study.
Article in Frontiers in endocrinology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Estimated glucose disposal rate and severe abdominal aortic calcification: evidence from a nationally representative study with external validation.Frontiers in nutrition · 2026Article
- Association between estimated glucose disposal rate and diabetes mellitus incidence in middle-aged and elderly adults and development of predictive model: evidence from two prospective longitudinal studies.BMC endocrine disorders · 2025Article
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Authors and funding
6 authors.
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Abstract
Purpose: The estimated glucose disposal rate (eGDR) serves as a straightforward and noninvasive indicator of insulin resistance (IR). This study aims to explore the association between eGDR and the risk of abdominal aortic calcification (AAC). Methods: We utilized data from adult participants (≥40 years old, n=3006) from the 2013-2014 National Health and Nutrition Examination Survey (NHANES) database. AAC was measured by dual-energy X-ray absorptiometry and quantified using the Kauppila score. Severe AAC (SAAC) was defined as an AAC score > 6. Logistic regression, restricted cubic spline (RCS), and subgroup analysis were used to analyze the relationship between eGDR and SAAC risk. Results: In fully adjusted models, eGDR was found to be negatively associated with SAAC (OR=0.86, 95%CI:0.79-0.94, Conclusions: The degree of IR assessed by eGDR is associated with SAAC risk. The eGDR shows promise as an epidemiological tool for evaluating the influence of IR on AAC.
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