Evidence map›Paper›PMID 40421186›Full record

ArticleRespirology case reports2025

Dual Immunotherapy for Pericardial Mesothelioma That Developed After a Decade-Long Idiopathic Pericarditis: A Case Report.

Beatriz Grau Mirete, Paula Rodriguez Paya, Mariano Martinez Marin, Asia Ferrández Arias, Miguel Borregón Rivilla, Antonio David Lazaro Sanchez, Pedro Morillas Blasco, Alvaro Rodriguez-Lescure, Javier David Benítez Fuentes

Abstract read
In one paragraph

Article in Respirology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Review
  2. Article
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Beatriz Grau MireteDepartment of Medical Oncology Hospital General Universitario de Elche, FISABIO Elche Spain.
Paula Rodriguez PayaDepartment of Medical Oncology Hospital General Universitario de Elche, FISABIO Elche Spain.
Mariano Martinez MarinDepartment of Medical Oncology Hospital General Universitario de Elche, FISABIO Elche Spain.
Asia Ferrández AriasDepartment of Medical Oncology Hospital General Universitario de Elche, FISABIO Elche Spain.
Miguel Borregón RivillaDepartment of Medical Oncology Hospital General Universitario de Elche, FISABIO Elche Spain.
Antonio David Lazaro SanchezDepartment of Medical Oncology Hospital General Universitario Morales Meseguer Murcia Spain.
Pedro Morillas BlascoDepartment of Cardiology Hospital General Universitario de Elche Elche Spain.
Alvaro Rodriguez-LescureDepartment of Medical Oncology Hospital General Universitario de Elche, FISABIO Elche Spain.
Javier David Benítez FuentesDepartment of Medical Oncology Hospital General Universitario de Elche, FISABIO Elche Spain.ORCID https://orcid.org/0000-0001-8827-2497

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Malignant pericardial mesothelioma (MPeM) is exceptionally rare, and its association with long-standing idiopathic pericarditis remains unreported. We present a 46-year-old woman with a decade-long history of recurrent idiopathic pericarditis who developed multiple pericardial nodules, mediastinal lymphadenopathy, and metastatic liver and bone lesions. A core needle biopsy confirmed biphasic MPeM. Due to her pericardial condition, she initially received platinum-based chemotherapy instead of immunotherapy, but the disease progressed. She then underwent dual immune checkpoint inhibition (ICI) and achieved a significant clinical and radiological response. This case raises the possibility of chronic inflammation contributing to pericardial malignancy and underscores the potential role of dual ICI in this rare and challenging disease.

Indexed as

case reportdual immunotherapyidiopathic pericarditisimmune checkpointpericardial mesothelioma

Identifiers

PMID40421186
PMCPMC12104722

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.