Evidence map›Paper›PMID 40421113›Full record

ReviewFrontiers in bioengineering and biotechnology2025

Innovative hydrogels in cutaneous wound healing: current status and future perspectives.

Prasad Sawadkar, Ferdinand Lali, Elena Garcia-Gareta, Beatriz Gil Garrido, Abdullah Chaudhry, Priya Matharu, Christos Kyriakidis, Karin Greco

Abstract readReview
In one paragraph

Review in Frontiers in bioengineering and biotechnology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 20 papers.

0numbers the graph read from it
0cells of the map it votes in
20citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

20 citing papers in PubMed.

  1. Review
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  15. Impact of CeOGels (Basel, Switzerland) · 2025
    Article
  16. Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

8 authors.

Prasad SawadkarThe Griffin Institute - Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospitals, London, United Kingdom.
Ferdinand LaliThe Griffin Institute - Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospitals, London, United Kingdom.
Elena Garcia-GaretaRegenerative Biomaterials Group, The RAFT Institute and The Griffin Institute, Northwick Park and Saint Mark's Hospital, London, United Kingdom.
Beatriz Gil GarridoThe Griffin Institute - Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospitals, London, United Kingdom.
Abdullah ChaudhryThe Griffin Institute - Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospitals, London, United Kingdom.
Priya MatharuThe Griffin Institute - Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospitals, London, United Kingdom.
Christos KyriakidisThe Griffin Institute - Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospitals, London, United Kingdom.
Karin GrecoThe Griffin Institute - Northwick Park Institute for Medical Research, Northwick Park and St Mark's Hospitals, London, United Kingdom.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Chronic wounds pose a substantial burden on healthcare systems, necessitating innovative tissue engineering strategies to enhance clinical outcomes. Hydrogels, both of natural and synthetic origin, have emerged as versatile biomaterials for wound management due to their structural adaptability, biocompatibility, and tunable physicochemical properties. Their hydrophilic nature enables efficient nutrient transport, waste removal, and cellular integration, while their malleability facilitates application to deep and irregular wounds, providing an optimal microenvironment for cell adhesion, proliferation, and differentiation. Extracellular matrix (ECM)- based hydrogels retain bioactive molecules that support cellular infiltration, immune modulation, and tissue remodelling, making them highly effective scaffolds for growth factor delivery and regenerative therapies. Additionally, their injectability and potential for

Indexed as

biomaterialschronic woundsextracellular matrixinjectable hydrogelspolymerswound healing

Identifiers

PMID40421113
PMCPMC12104307

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.