A journey with Maffucci syndrome: From skull base chondrosarcoma to multiorgan management: A case report and literature review.

Jana Dibas, Aseel Eid, Somaya Al Kiswani, Zaid Sawaftah, Nader Sarhan, Abdullah Nofal, Omar Sawafta, Jehad Khamaysa

Abstract readCase Reports

In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

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1citing papers in PubMed

–field-weighted citation impact

1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

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3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

Papillary Thyroid Carcinoma, Bilateral Macronodular Adrenal Cortical Disease-Related Cortisol Excess, and Femoral Enchondroma: A Novel Phenotype-Genotype Based on Next-Generation Sequencing (Variants ofDiagnostics (Basel, Switzerland) · 2026
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5 · Who and what money

Authors and funding

8 authors.

Jana DibasDepartment of Medicine, An Najah National University, Nablus, Palestine.

Aseel EidDepartment of Medicine, An Najah National University, Nablus, Palestine.

Somaya Al KiswaniRadiology Department, King Hussein Cancer Center, Amman, Jordan.

Zaid SawaftahDepartment of Medicine, An Najah National University, Nablus, Palestine.

Nader SarhanRadiology Department, King Hussein Cancer Center, Amman, Jordan.

Abdullah NofalRadiology Department, King Hussein Cancer Center, Amman, Jordan.

Omar SawaftaDepartment of Medicine, An Najah National University, Nablus, Palestine.

Jehad KhamaysaDepartment of Radiology, Tubas Turkish Governmental Hospital, Tubas, Palestine.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Maffucci syndrome is a very infrequently occurring genetic disorder. The 2 classic findings are enchondromas and hemangiomas with a high propensity to become malignant, leading to the formation of chondrosarcomas. In this study, we present the case of a 30-year-old male patient diagnosed with chondrosarcoma at the base of the skull related to Maffucci syndrome who presented with disturbances in visual perception and a palsy of the cranial nerve VI. His imaging studies confirmed the diagnosis; treatment included subtotal resection followed by radiation therapy. The following is the case that epitomizes the dreaded complications of Maffucci syndrome and the need for multidisciplinary, attentive follow-up to find early signs of malignant transformation.

Indexed as

EnchondromaHemangiomaMaffucci syndromeSkull base chondrosarcoma

Identifiers

PMID40420921

DOI10.1016/j.radcr.2025.04.027

PMCPMC12104684

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