Evidence map›Paper›PMID 40420920›Full record

ArticleRadiology case reports2025

Pulmonary lymphangioleiomyomatosis (LAM) having no extra-pulmonary manifestations with chemical and mechanical pleurodesis: A case report and review of literature.

Mustafa Shehzad, Beenish Sabir, Dawood Shehzad, Haris Mumtaz Malik, Anurag Jha, Muhammad Nabeel Saddique, Javed Iqbal

Abstract readCase Reports
In one paragraph

Article in Radiology case reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Mustafa ShehzadHackensack University Medical Center, New Jersey, United States.
Beenish SabirRawalpindi Medical University, Rawalpindi, Pakistan.
Dawood ShehzadUniversity of South Dakota, Department of Internal Medicine, South Dakota, United States.
Haris Mumtaz MalikRawalpindi Medical University, Rawalpindi, Pakistan.
Anurag JhaDepartment of Nursing, Hamad Medical Corporation, Doha, Qatar.
Muhammad Nabeel SaddiqueDepartment of Nursing, Hamad Medical Corporation, Doha, Qatar.
Javed IqbalHamad Medical Corporation, Doha, Qatar.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Lymphangioleiomyomatosis (LAM) is a rare, progressive lung disease characterized by abnormal smooth muscle proliferation, leading to cystic destruction of the lung parenchyma. We present the case of a female in her early 40s who presented with intermittent chest pain for 1 month. Imaging revealed left hydropneumothorax with multiple bilateral pulmonary parenchymal cysts, and a subsequent lung biopsy confirmed the diagnosis of pulmonary LAM. The patient underwent video-assisted thoracoscopic surgery (VATS) with mechanical and chemical pleurodesis. Given her stable condition, no immediate sirolimus therapy was initiated, and close follow-up with serial imaging was planned. This case highlights the diagnostic challenges of LAM, especially with low VEGF-D levels, and underscores the role of pleurodesis as a management option in select patients. Early recognition and tailored management are essential to optimize patient outcomes.

Indexed as

Case reportImmunohistochemistryLung diseasesLymphangioleiomyomatosisPleural effusionPleurodesis

Identifiers

PMID40420920
PMCPMC12104686

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