Evidence map›Paper›PMID 40420870›Full record

ArticleIndian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India2025

Salivary Gland Scintigraphy in Parotid-Sparing IMRT for H&N Cancer: Trend of Function Recovery.

Alessia Reali, Tiziana Angusti, Edoardo Trevisiol, Simona Allis, Roberta Verna, Lavinia Bianco, Maria Grazia Ruo Redda

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In one paragraph

Article in Indian journal of otolaryngology and head and neck surgery : official publication of the Association of Otolaryngologists of India, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Alessia RealiRadiation Oncology Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.ORCID 0009-0008-3690-8367
Tiziana AngustiNuclear Medicine Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Edoardo TrevisiolRadiation Oncology Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Simona AllisRadiation Oncology Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Roberta VernaRadiation Oncology Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Lavinia BiancoRadiation Oncology Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.
Maria Grazia Ruo ReddaRadiation Oncology Unit, Department of Oncology, University of Turin, S. Luigi Hospital, Orbassano, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The recovery of parotid gland function following radiotherapy for head and neck (H&N) cancer has a significant impact on the quality of life (QOL) of patients, with strong correlations between salivary output and mean radiation dose received by the parotid glands. Salivary gland scintigraphy (SGdS) is a valuable tool for assessing salivary gland functionality. Our case reports demonstrates that parotid glands that were spared during RT undergo a transitional phase of hypofunctionality as observed in SGdS assessments. These findings suggest that even spared parotid glands may experience temporary functional impairment, which could have implications for patient management and expectations for recovery post-treatment. Supplementary Information: The online version contains supplementary material available at 10.1007/s12070-025-05401-y.

Indexed as

H&N-cancerH&N intensity modulated radiotherapyParotids glandssparingSalivary gland scintigraphySalivary glands function

Identifiers

PMID40420870
PMCPMC12103443

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.