ArticleEndocrinology, diabetes & metabolism2025
Investigating the Relationship Between Serum Uric Acid and Dyslipidemia in Young Adults in Bangladesh.
Article in Endocrinology, diabetes & metabolism, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
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Who cites it
4 citing papers in PubMed.
- Mediating effect of serum lipids on the BMI-uric acid association: A cross-sectional study.Medicine · 2026Article
- Interactions between serum uric acid and gut microbiota: implications for metabolic health.Metabolism open · 2026Review
- Serum uric acid and its association with general and abdominal obesity and elevated blood pressure among young adults in Sylhet division, Bangladesh.BMC endocrine disorders · 2026Article
- Lipid-Derived Cardiometabolic Indices in Normouricemic and Hyperuricemic Adults: A Retrospective Cross-Sectional Association Study.Healthcare (Basel, Switzerland) · 2025Article
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Authors and funding
7 authors.
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Abstract
objectivesWhile some reports exist on the relationship between serum uric acid (SUA) and dyslipidemia in adults, there is limited information available regarding young adults. This study aimed to evaluate the relationship between SUA and dyslipidemia, as well as its components, among young adults in Bangladesh.
methodsThis study consisted of 458 participants (281 male and 177 female) aged between 18 and 30 years. The levels of SUA, fasting blood glucose and lipid profile (TG, TC, HDL-C and LDL-C) were measured using standard colorimetric methods. Bivariate logistic regression modelling was used to examine the relationship between SUA and dyslipidemia and its components.
resultsThe overall prevalence of hyperuricemia was 24% with 27.6% in males and 18.6% in females. Males had a higher mean SUA level (6.6 ± 1.5 mg/dL) than females (5.3 ± 1.2 mg/dL) (p < 0.001). The prevalence of dyslipidemia was 74.2% with 83.2% in male and 59.8% in female subjects. The prevalence of hypertriglyceridemia, hypercholesterolemia, high LDL-C and low HDL-C was 30.1%, 26.2%, 28.8% and 64.8%, respectively. There was an increasing trend in the level and prevalence of elevated lipid profile markers across the SUA quartiles (p < 0.001). SUA level showed a positive correlation with TG, TC and LDL-C and a negative correlation with HDL (p < 0.001). In regression analysis, a significant association was found between SUA and dyslipidemia in all participants as well as in the male-female groups separately (at least p < 0.05). Furthermore, a significant association (p < 0.001) was found between SUA and individual lipid components in the regression models.
conclusionDyslipidemia and its components were more prevalent in individuals with hyperuricemia than in those without. This study identified a significant association between SUA and dyslipidemia in young adults in Bangladesh. Further research is needed to explore the mechanisms behind this association.
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