Evidence map›Paper›PMID 40420784›Full record

ReviewCurrent organic synthesis2025

Chitosan-based Nano/Biomaterials in Bone Tissue Engineering and Regenerative Medicine: Recent Progress and Advances.

Taha Jafari, Seyed Morteza Naghib, M R Mozafari

Abstract readReview
PubMed Publisher
In one paragraph

Review in Current organic synthesis, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Taha JafariNanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran, 1684613114, Iran.
Seyed Morteza NaghibNanotechnology Department, School of Advanced Technologies, Iran University of Science and Technology (IUST), Tehran, 1684613114, Iran.
M R MozafariAustralasian Nanoscience and Nanotechnology Initiative (ANNI), Monash University LPO, Monash Institute of Medical Research, Clayton, VIC 3168, Australia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

The biopolymer chitosan, which is derived from chitin, has shown great promise for tissue regeneration and regulated drug delivery. Its broad-spectrum antibacterial action, low toxicity, biocompatibility, and many other attributes make it appealing for use in biomedical applications. Crucially, chitosan may be synthesized into a range of forms that can be customized to provide desired results, such as hydrogels, membranes, scaffolds, and nanoparticles. Hydrogels that are biocompatible and self-healing are innovative soft materials with considerable potential for use in biomedical applications. Hydrogels that self-heal using chitosan, which are mostly made by dynamic imine linkages, have gained a lot of interest because of their great biocompatibility, moderate preparation requirements, and capacity to mend themselves in a physiological setting. In this study, a summary of the applications of chitosan-based self-healing hydrogels in bone, cartilage, and tooth tissue regeneration and drug delivery is provided. Lastly, we have mentioned the difficulties and potential outcomes for the biomedical field's creation of hydrogels based on chitosan that can mend themselves.

Indexed as

Biocompatible MaterialsBone and BonesChitosanNanoparticlesRegenerative MedicineTissue EngineeringAnimalsBone RegenerationDrug Delivery SystemsHumansHydrogelsTissue ScaffoldsBiocompatible MaterialsChitosanHydrogelsbiocompatibility.boneChitosanhydrogelnatural polymertissue engineering

Identifiers

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.