Evidence map›Paper›PMID 40420245›Full record

ArticleJournal of orthopaedic surgery and research2025

Complex primary total knee arthroplasty with constrained condylar knee in post-traumatic arthritis: a retrospective comparison between 3D-printed patient-specific instrumentation and conventional instrumentation.

Weikun Zheng, Junfen Tang, Junhao Li, Jieying Huang, Jianwei Wang, Wende Xiao, Xinliang Wang

Abstract readComparative Study
In one paragraph

Article in Journal of orthopaedic surgery and research, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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4 · The record

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5 · Who and what money

Authors and funding

7 authors.

Weikun ZhengDepartment of Orthopedics, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Junfen TangDepartment of Neurology, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Junhao LiDepartment of Orthopedics, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Jieying HuangDepartment of Orthopedics, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China.
Jianwei WangDepartment of Orthopedics, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China. 13316188653@189.cn.
Wende XiaoDepartment of Orthopedics, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China. eyxiaowende@scut.edu.cn.
Xinliang WangDepartment of Orthopedics, Guangzhou First People's Hospital, School of Medicine, South China University of Technology, Guangzhou, Guangdong, China. wxl_371543582@qq.com.

Funding

Nansha District livelihood Science and Technology Program of Guangzhou City 2023MS011
6 · The paper itself

Abstract

backgroundComplex primary total knee arthroplasty (TKA) using constrained implants for post-traumatic arthritis (PTA) presents significant surgical challenges and is associated with higher complication rates compared to routine TKA procedures. This study aimed to analyze the demographic characteristics and operative details of patients undergoing complex primary TKA with constrained condylar knee (CCK) implants following intra- or extra-articular peri-knee fractures and to compare short- to medium-term clinical outcomes between three-dimensional (3D)-printed patient-specific instrumentation (PSI) and conventional instrumentation in these procedures.

methodsWe conducted a retrospective analysis of patients who underwent complex primary CCK-TKA for post-traumatic arthritis using either 3D-printed PSI or conventional instrumentation at our institution between January 2015 and December 2020. Demographic data, perioperative parameters, radiographic outcomes, and clinical efficacy measures were compared between the two groups. Complications were recorded, and implant survival rates were calculated.

resultsThe study included 55 patients with a mean follow-up of 82 months (range 49-109). A notable prevalence of severe preoperative valgus deformity was observed (26/55, 47.27%), and regression analysis identified a history of lateral compartment fracture as an independent risk factor for the development of valgus deformity (OR 6.28, 95% CI 1.40-28.30, P = 0.017). Compared to the conventional group (n = 26), the PSI group (n = 29) demonstrated significantly shorter operative time, reduced blood loss, improved postoperative mechanical alignment, and superior final follow-up scores for range of motion (ROM) and Hospital for Special Surgery (HSS) knee scores. Wound complications occurred in 1 case in the PSI group versus 7 cases in the conventional group. One patient in the conventional group required reoperation due to infection and patellar osteonecrosis. Both groups maintained 100% implant survival (revision-free) at final follow-up.

conclusionSevere valgus deformity appears to be a key indication for constrained implants in this population, and a history of lateral tibial plateau fracture may contribute to the development of valgus deformity prior to TKA. CCK-TKA proves to be a safe and effective method for managing complex PTA. Our findings suggest that 3D-printed PSI may enhance surgical precision, reduce operative trauma, and improve radiographic and clinical outcomes in the short to medium term compared to conventional techniques.

Indexed as

ArthritisArthroplasty, Replacement, KneeKnee InjuriesKnee JointKnee ProsthesisOsteoarthritis, KneePrinting, Three-DimensionalAdultAgedAged, 80 and overFemaleHumansMaleMiddle AgedPostoperative ComplicationsProsthesis DesignComplex primary total knee arthroplastyConstrained condylar kneePatient-specific instrumentationPost-traumatic arthritisValgus deformity

Identifiers

PMID40420245
PMCPMC12107906

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.