ArticleActa veterinaria Scandinavica2025
Genetic analyses of lumbosacral transitional vertebra and hip dysplasia in nine dog breeds in Norway.
Article in Acta veterinaria Scandinavica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.
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Who cites it
2 citing papers in PubMed.
- Congenital and Breed-Associated Vertebral Anomalies in Dogs and Cats: Developmental Anatomy, Genetic Determinants, and Biological Significance.Life (Basel, Switzerland) · 2026Review
- Prevalence of lumbosacral transitional vertebrae and association with hip dysplasia in Rhodesian Ridgebacks in Germany.Veterinarni medicina · 2025Article
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Authors and funding
5 authors.
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Abstract
backgroundA lumbosacral transitional vertebra (LTV) is a congenital anomaly with reported prevalences ranging from 0 to 67% in different dog breeds, implying possible genetic differences. LTV has been associated with canine hip dysplasia (CHD) and degenerative lumbosacral stenosis (DLSS). Genetic parameters, including heritability estimates, are important for understanding the genetic influence on specific traits and for evaluating the effectiveness of possible genetic selection in reducing the prevalence of disorders. This study aimed to determine the heritability of LTV in nine dog breeds in Norway and estimate the genetic correlation with CHD.
resultsThe heritability estimates for LTV across the nine breeds ranged from low to moderate (0.056-0.314), while the heritability estimates for CHD were moderate to high (0.254-0.580). The estimates of genetic correlations between the two traits were mostly non-significant and varied strongly among breeds in size and direction.
conclusionsThis study indicated that genetic factors influence LTV in several breeds and that there is a potential to reduce the prevalence by genetic selection, even if the heritability estimates of LTV ranged from low to moderate. The heritability estimates of CHD were within the range reported earlier, ranging from moderate to high. There was no general indication of a genetic correlation between LTV and CHD across breeds.
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