Evidence map›Paper›PMID 40420139›Full record

ArticleBiomedical engineering online2025

Enhancing laparoscopic visibility: efficient surgical smoke clearance innovatively using nebulization technology.

Xiaosong Lin, Qiming Fan, Renjie Li, Ruijian Chen, Zifeng Yang, Yong Li

Abstract read
In one paragraph

Article in Biomedical engineering online, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Xiaosong Lin *Department of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Qiming Fan *Department of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Renjie Li *Department of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Ruijian ChenDepartment of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China.
Zifeng YangDepartment of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. yangzifeng@gdph.org.cn.
Yong LiDepartment of Gastrointestinal Surgery, Department of General Surgery, Guangdong Provincial People's Hospital (Guangdong Academy of Medical Sciences), Southern Medical University, Guangzhou, 510080, China. liyong@gdph.org.cn.

Funding

National Natural Science Foundation of China 32370836Natural Science Foundation of Guangdong Province 2023A1515110294NSFC Incubation Project of Guangdong Provincial People's Hospital KY0120220049
6 · The paper itself

Abstract

backgroundParticulate matter (PM) in surgical smoke is known to influence operative vision and poses safety risks to operating personnel. Nebulization, which is effective in promoting the deposition of PM, has not been used to clear laparoscopic surgical smoke.

methodsThe novel nebulizer was tested for mechanical characteristics and applied to evaluate its feasibility for surgical smoke clearance. Nebulization (n = 6) or elimination (n = 6) procedures were performed to manage surgical smoke produced by electrocautery hook or ultrasonic scalpel on various tissues of twelve rabbits. Levels of PM in surgical smoke, including the PM1.0, PM2.5, PM10, and total suspended particulate were compared to evaluate emissions from both surgical instruments. In addition, pre-treatment, post-treatment and reduction in PM concentrations were compared between the nebulization and elimination groups.

resultsThe spray cone angle was approximately 70°, and the median particle size was around 25 µm. Laparoscopic visibility was restored with clearance of surgical smoke within 8 s after nebulization. The electrocautery hook produced significantly higher levels of PM compared to the ultrasonic scalpel. The PM concentrations generated by electrocautery hook varied across different tissues, whereas only PM1.0 level differed with the ultrasonic scalpel. The pre-treatment PM concentrations were comparable between both groups. The nebulization group showed a greater reduction in PM concentrations compared to the elimination group, with statistical significance in PM1.0 levels. Consequently, post-treatment PM concentrations were significantly lower in the nebulization group. Similar trends were observed across all target tissues except for omentum.

conclusionsNebulization was an effective method for clearing laparoscopic surgical smoke thereby improving surgical vision and potentially mitigating risks associated with surgical smoke exposure.

Indexed as

LaparoscopyNebulizers and VaporizersSmokeAnimalsParticle SizeParticulate MatterRabbitsParticulate MatterSmokeLaparoscopic surgeryNebulizationParticulate matterSurgical smokeVision

Identifiers

PMID40420139
PMCPMC12105325

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.