Evidence map›Paper›PMID 40420083›Full record

ArticleBMC oral health2025

A comparative analysis of deep learning models for assisting in the diagnosis of periapical lesions in periapical radiographs.

Jian Liu, Chaoran Jin, Xiaolan Wang, Kexu Pan, Zhuoyang Li, Xinxuan Yi, Yu Shao, Xiaodong Sun, Xijiao Yu

Abstract readComparative Study
In one paragraph

Article in BMC oral health, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 10 papers, 1 of them a synthesis that pooled it.

0numbers the graph read from it
0cells of the map it votes in
10citing papers in PubMed, 1 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

10 citing papers in PubMed, 1 synthesis or guideline pooled it.

  1. Pooled it
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Jian Liu *School of Stomatology, Shandong Second Medical University, Weifang, 261053, Shandong, China.
Chaoran Jin *School of Stomatology, Shandong Second Medical University, Weifang, 261053, Shandong, China.
Xiaolan Wang *School of Stomatology, Shandong Second Medical University, Weifang, 261053, Shandong, China.
Kexu PanSchool of Stomatology, Shandong Second Medical University, Weifang, 261053, Shandong, China.
Zhuoyang LiSchool of Stomatology, Shandong Second Medical University, Weifang, 261053, Shandong, China.
Xinxuan YiSchool of Stomatology, Shandong Second Medical University, Weifang, 261053, Shandong, China.
Yu ShaoShandong Xintai Huizhi Health and Medical Big Data Co., Ltd., Jinan, 250001, Shandong Province, China.
Xiaodong SunShungeng Branch, Central Laboratory, Jinan Stomatological Hospital, Jinan Key Laboratory of oral tissue regeneration, Shandong Provincial Health Commission Key Laboratory of Oral Diseases and Tissue Regeneration, Jinan, 250001, Shandong Province, China. sunxiaodong618@126.com.
Xijiao YuSchool of Stomatology, Shandong Second Medical University, Weifang, 261053, Shandong, China. yayiyu@163.com.

Funding

Jinan Medical and Health Science and Technology Big Data Development Plan 2022-YBD-17Jinan Medical and Health Science and Technology Big Data Development Plan 2023-YBD-1-08Jinan Municipal Science and Technology Plan Project 202430028
6 · The paper itself

Abstract

purposeNumerous studies have investigated the use of convolutional neural network (CNN) models for detecting periapical lesions(PLs). However, limited research has focused on evaluating their potential in assisting clinicians with diagnosis. This study aims to utilize two deep learning(DL) models, ConvNeXt and ResNet34, to aid novice dentists in the detection of PLs on periapical radiographs (PRs). By assessing the diagnostic support provided by these models, this research seeks to promote the clinical application of DL in dentistry. MATERIALS AND

methodsIn this study, 1,305 PRs were gathered and then split into a training set of 1,044 images and a validation set of 261 images, following an 80/20 ratio. The model's effectiveness was assessed using various measures, including precision, sensitivity, F1 score, specificity, accuracy, and the area under the curve (AUC). To evaluate the impact of the model on diagnostic performance by novice dentists, we used an additional set of 800 individual teeth PRs, which were not included in the training or validation sets. The diagnostic performance and time of three novice dentists were measured both with and without model assistance.

resultsThe precision of ConvNeXt was 85.93%, with an F1 score of 0.92, accuracy of 91.25%, sensitivity of 98.49%, specificity of 84.11%, and an AUC of 0.9693, outperforming ResNet34 across all metrics. In comparison, ResNet34 achieved a precision of 83.08%, an F1 score of 0.84, accuracy of 81.63%, sensitivity of 84.38%, specificity of 78.13%, and an AUC of 0.8988. In the model-assisted diagnosis phase, both ConvNeXt and ResNet34 improved the diagnostic performance of novice dentists. With the help of ConvNeXt, the average AUC of three dentists increased from 0.88 to 0.94, while with ResNet34, the average AUC of the three dentists improved from 0.88 to 0.91. ConvNeXt performed better than ResNet34 (p < 0.05). Additionally, ConvNeXt reduced the average diagnostic time of the three dentists from 178.8 min to 141.9 min, while ResNet34 reduced the average diagnostic time from 178.8 min to 153.6 min.

conclusionConvNeXt significantly improved the diagnostic performance of novice dentists and reduced the time required for diagnosis, thereby enhancing clinical efficiency in both diagnosis and treatment. This model shows potential for application in dental clinics or educational institutions where experienced specialists are limited, but there is a large presence of novice, less-experienced dentists.

Indexed as

Deep LearningPeriapical DiseasesRadiography, DentalHumansNeural Networks, ComputerSensitivity and SpecificityConvNeXtDeep learningPeriapical lesionPeriapical radiographsResNet34

Identifiers

PMID40420083
PMCPMC12107815

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.