Evidence map›Paper›PMID 40420080›Full record

ArticleBMC medical ethics2025

Ethical and social considerations of applying artificial intelligence in healthcare-a two-pronged scoping review.

Emanuele Ratti, Michael Morrison, Ivett Jakab

Abstract readScoping Review
In one paragraph

Article in BMC medical ethics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 23 papers, 3 of them syntheses that pooled it.

0numbers the graph read from it
0cells of the map it votes in
23citing papers in PubMed, 3 pooled it
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

23 citing papers in PubMed, 3 syntheses or guidelines pooled it.

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  12. [Application and progress of artificial intelligence agents in drug development].Zhejiang da xue xue bao. Yi xue ban = Journal of Zhejiang University. Medical sciences · 2026
    Review
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  17. Design biology and mind-body health.Journal, genetic engineering & biotechnology · 2025
    Review
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

3 authors.

Emanuele RattiDepartment of Philosophy, Cotham House University of Bristol, Bristol, BS6 6JL, UK.ORCID 0000-0003-1409-8240
Michael MorrisonHelex - Centre for Health, Law and Emerging Technologies, Faculty of Law, University of Oxford, St Cross Building, Room 201St Cross Road, Oxford, OX1 3UL, UK. michael.morrison@law.ox.ac.uk.ORCID 0000-0001-6870-6673
Ivett JakabYAGHMA B.V., 6C , Poortweg, Delft, Netherlands.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundArtificial Intelligence (AI) is being designed, tested, and in many cases actively employed in almost every aspect of healthcare from primary care to public health. It is by now well established that any application of AI carries an attendant responsibility to consider the ethical and societal aspects of its development, deployment and impact. However, in the rapidly developing field of AI, developments such as machine learning, neural networks, generative AI, and large language models have the potential to raise new and distinct ethical and social issues compared to, for example, automated data processing or more 'basic' algorithms.

methodsThis article presents a scoping review of the ethical and social issues pertaining to AI in healthcare, with a novel two-pronged design. One strand of the review (SR1) consists of a broad review of the academic literature restricted to a recent timeframe (2021-23), to better capture up to date developments and debates. The second strand (SR2) consists of a narrow review, limited to prior systematic and scoping reviews on the ethics of AI in healthcare, but extended over a longer timeframe (2014-2024) to capture longstanding and recurring themes and issues in the debate. This strategy provides a practical way to deal with an increasingly voluminous literature on the ethics of AI in healthcare in a way that accounts for both the depth and evolution of the literature.

resultsSR1 captures the heterogeneity of audience, medical fields, and ethical and societal themes (and their tradeoffs) raised by AI systems. SR2 provides a comprehensive picture of the way scoping reviews on ethical and societal issues in AI in healthcare have been conceptualized, as well as the trends and gaps identified.

conclusionOur analysis shows that the typical approach to ethical issues in AI, which is based on the appeal to general principles, becomes increasingly unlikely to do justice to the nuances and specificities of the ethical and societal issues raised by AI in healthcare, as the technology moves from abstract debate and discussion to real world situated applications and concerns in healthcare settings.

Indexed as

Artificial IntelligenceDelivery of Health CareHumansArtificial intelligenceHealthcareMedicineScoping review

Identifiers

PMID40420080
PMCPMC12107984

What OpenQuestion holds

Textmetadata
LicenceCC BY
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.