Evidence map›Paper›PMID 40420004›Full record

ArticleBMC pregnancy and childbirth2025

Effect of Hypertensive Disorders of Pregnancy (HDP) on maternal and perinatal birth outcomes in Eastern Ethiopia: a prospective cohort study.

Ebisa Zerihun, Firaol Girma, Nimona Amena, Wubet Tazeb Wondie, Belete Feyera Olkaba, Lemma Mideksa Egu, Solomon Seyife Alemu, Gemechu Gelan Bekele, Belay Tafa Regassa, Meseret Robi Tura and 1 more

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Article in BMC pregnancy and childbirth, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

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4 · The record

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PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Ebisa ZerihunDepartment of Nursing, College of Health Sciences, Oda Bultum University, Chiro, Ethiopia. ebisaz077@gmail.com.
Firaol GirmaDepartment of Nursing, College of Health Sciences, Oda Bultum University, Chiro, Ethiopia.
Nimona AmenaDepartment of Nursing, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Wubet Tazeb WondieDepartment of Pediatrics and Child Health Nursing, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Belete Feyera OlkabaDepartment of Public Health, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Lemma Mideksa EguDepartment of Nursing, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Solomon Seyife AlemuDepartment of Midwifery, College of Health Science Shashemene Campus, Madda Walabu University, Shashemene, Ethiopia.
Gemechu Gelan BekeleDepartment of Midwifery, College of Health Science Shashemene Campus, Madda Walabu University, Shashemene, Ethiopia.
Belay Tafa RegassaDepartment of Medical Laboratory Sciences, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Meseret Robi TuraDepartment of Nursing, College of Health Sciences and Referral Hospital, Ambo University, Ambo, Ethiopia.
Fekadu Abera KebedeDepartment of Nursing, College of Health Sciences, Oda Bultum University, Chiro, Ethiopia.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

backgroundGlobally, hypertensive disorders of pregnancy are the major causes of maternal and perinatal morbidity and mortality. In low and middle-income countries, including Ethiopia, studies on the effect of hypertensive disorders of pregnancy on maternal and perinatal birth outcomes are limited.

objectivesThe aim of this study was to examine the effect of hypertensive disorders of pregnancy on maternal and perinatal birth outcomes in Eastern Ethiopia.

methodsWe employed a prospective cohort study design involving 374 pregnant women, equally divided into hypertensive ((n = 187) and normotensive (n = 187). Data were collected face to face using an interviewer-administered questionnaire as well as by reviewing the medical records of the mothers. Data analysis was done in STATA Version 17. Binary logistic regression was run to produce risk ratios (relative risk) and 95% confidence intervals along with their p-values were calculated in the bivariate and multivariable analyses. Significance was declared at a P-value of less than 0.05.

resultsCompared with normotensive, women with hypertensive disorder had significantly increased risk of developing preterm birth (cRR = 1.8; 95% CI, 1.5, 2.2), stillbirth (cRR = 1.6; 95% CI, 1.3, 2.02), low birth weight (cRR = 1.9; 95% CI, 1.6, 2.3), and early neonatal death (cRR = 1.7; 95% CI, 1.3, 2.3). Women with hypertensive disorders had 2.6 times (aRR = 2.6, 95% CI; 1.2, 5.7) higher risk of perinatal death, and 1.7 (aRR = 1.7; 95%CI, 1.02, 2.90) times higher risk of cesarean section delivery compared with the normotensive women controlling the other variables.

conclusionSignificant risk of cesarean section delivery, perinatal death, stillbirth, low birth weight delivery, and early neonatal death were reported among women with hypertensive disorders of pregnancy. To minimize the burden of the problem, much has to be done by health care professionals and stakeholders focusing on the identification and proper management of mothers with hypertensive disorders.

Indexed as

Hypertension, Pregnancy-InducedPregnancy OutcomePremature BirthStillbirthAdultCesarean SectionEthiopiaFemaleHumansInfant, Low Birth WeightInfant, NewbornLogistic ModelsPerinatal MortalityPregnancyProspective StudiesRisk FactorsEthiopiaHypertensive disordersMaternal outcomePerinatal outcomePregnancyWest Hararghe

Identifiers

PMID40420004
PMCPMC12105356

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.