Evidence map›Paper›PMID 40419940›Full record

Trial reportBMC geriatrics2025

Long-term health conditions and their impact on people with sleep disturbances and dementia.

Penny Rapaport, Ankita Bhojwani, Lucy Webster, Sarah Amador, Malvika Muralidhar, Gill Livingston

Abstract readRandomized Controlled Trial
In one paragraph

Trial report in BMC geriatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. The DREAMS START intervention for sleep in dementia: Long-term follow-up of a randomized controlled trial.Alzheimer's & dementia : the journal of the Alzheimer's Association · 2026
    Trial
  2. Trial
  3. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Penny RapaportUCL Department of Mental Health of Older People, Division of Psychiatry, Wing B, Floor 6 Maple House, 149 Tottenham Court Rd, London, W1T 7NF, UK. P.Rapaport@ucl.ac.uk.
Ankita BhojwaniUCL Department of Mental Health of Older People, Division of Psychiatry, Wing B, Floor 6 Maple House, 149 Tottenham Court Rd, London, W1T 7NF, UK.
Lucy WebsterUCL Department of Mental Health of Older People, Division of Psychiatry, Wing B, Floor 6 Maple House, 149 Tottenham Court Rd, London, W1T 7NF, UK.
Sarah AmadorUCL Department of Mental Health of Older People, Division of Psychiatry, Wing B, Floor 6 Maple House, 149 Tottenham Court Rd, London, W1T 7NF, UK.
Malvika MuralidharUCL Department of Mental Health of Older People, Division of Psychiatry, Wing B, Floor 6 Maple House, 149 Tottenham Court Rd, London, W1T 7NF, UK.
Gill LivingstonUCL Department of Mental Health of Older People, Division of Psychiatry, Wing B, Floor 6 Maple House, 149 Tottenham Court Rd, London, W1T 7NF, UK.

Funding

Health Technology Assessment Programme NIHR HTA 128761
6 · The paper itself

Abstract

backgroundSleep disturbances are common for people with dementia and can be distressing for them and their family. People with dementia live with an average of five other long-term conditions (LTCs). Little is known about the impact of LTCs on dementia and sleep. We aimed to explore this within the DREAMS START (Dementia Related Manual for Sleep; Strategies for relatives) trial of a multi-component intervention delivered to family carers, to consider how symptoms of LTCs impacted on carer ability to implement DREAMS START intervention strategies.

methodWe conducted a qualitative interview study recruited participants from the intervention arm of the DREAMS START trial in English NHS sites. Participants were 17 family carers of people with dementia, other LTCs and sleep disturbances. We used a semi-structured topic guide and conducted interviews, analysed using reflective thematic analysis.

resultsWe identified two overarching themes. Firstly, there was a complex interaction of LTCs, sleep and dementia. LTCs including pain, interacted with dementia symptoms to worsen sleep and physical symptoms. Carers reported dilemmas about whether to give analgesia, primarily understanding their relatives' sleep disturbances in terms of dementia diagnosis. Secondly carers were exhausted from lack of sleep and physical health difficulties made it harder to, for example, increase daytime activity for their relative.

conclusionsThere is a complex relationship between LTCs, dementia and sleep and the effect of LTCs in someone with dementia may be underestimated. It is important that families know that people with dementia need adequate analgesia. In addition, tiredness and illness in family carers may mean they need support to implement strategies, or they will be unable to break the cycle of exhaustion.

Indexed as

CaregiversDementiaHealth StatusSleep Wake DisordersAgedAged, 80 and overChronic DiseaseFemaleHumansMaleMiddle AgedTime FactorsCarersDementiaDiabetesLong-term conditionsPainQualitativeSleep

Identifiers

PMID40419940
PMCPMC12105245

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.