Evidence map›Paper›PMID 40419730›Full record

ArticleThe European journal of health economics : HEPAC : health economics in prevention and care2025

Investment gaps in antimicrobial resistance research & development: trends in Europe, 2017-2021.

Elisa Fabbro, Usha Lamichhane, Ralf Sudbrak, Lesley Ogilvie, Antonio Vitiello, Andrea Zovi, Michela Sabbatucci

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Article in The European journal of health economics : HEPAC : health economics in prevention and care, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Elisa Fabbro *Area Science Park, Padriciano 99, 34149, Trieste, Italy.
Usha Lamichhane *Global AMR R&D Hub, Schlüterstrasse 39, 10629, Berlin, Germany.
Ralf SudbrakGlobal AMR R&D Hub, Schlüterstrasse 39, 10629, Berlin, Germany.
Lesley OgilvieGlobal AMR R&D Hub, Schlüterstrasse 39, 10629, Berlin, Germany.
Antonio VitielloMinistry of Health, Viale Giorgio Ribotta 5, 00144, Rome, Italy. avitiello@hotmail.it.
Andrea ZoviMinistry of Health, Viale Giorgio Ribotta 5, 00144, Rome, Italy. zovi.andrea@gmail.com.ORCID http://orcid.org/0000-0002-6528-2171
Michela SabbatucciNational Institute of Health, Viale Regina Elena 299, 00161, Rome, Italy.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionAntimicrobial resistance (AMR) remains one of the world's most pressing health, economic, and social challenges. To combat this crisis, innovative tools have been developed to enhance research and development (R&D) efforts like the Global AMR R&D Hub's Dynamic Dashboard. By aggregating data from projects worldwide, the Dynamic Dashboard highlights trends and gaps in AMR R&D investments, totalling more than 8.22 billion Euros in the period 2017-2021 across the One Health continuum - human, animal, plant and environment. Launched in March 2020, the Dynamic Dashboard supports global priority setting and decision-making in AMR research, fostering strategic planning to promote efficient use of international resources and cross sectoral collaboration in AMR R&D.

methodsRecognizing the urgent need for innovative diagnostics, treatments, and prevention strategies against AMR, here we presented a comprehensive analysis of public and philanthropic investments in AMR R&D obtained from January 2017 to December 2021 across Europe.

resultsWe calculated the investments by One Health sector, year of funding, gross domestic product (GDP), research area, type of project, and infectious agent to raise awareness and promote global visibility of the R&D landscape in Europe. Our analysis revealed limited AMR R&D investments in the non-human sectors and non-bacterial topics, geographical polarization of funders, and some unaligned trends between the amount of investments and number of projects funded over the study period. DISCUSSION: Harnessing these data-driven insights, we aimed to inform stakeholders and optimize the allocation of economic resources for AMR R&D. Prioritizing unmet needs with the greatest potential for impact in this field will expedite the development of effective solutions to mitigate the global threat of AMR.

Indexed as

Biomedical ResearchDrug Resistance, MicrobialInvestmentsResearchAnti-Bacterial AgentsEuropeHumansAnti-Bacterial AgentsAMRAntimicrobial-resistanceDynamic DashboardEuropeGlobal AMR R&D HubInvestmentsR&D

Identifiers

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.