ArticleScientific reports2025
Trends in age at natural menopause and menarche and related factors in Iran: results from a population-based study.
Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers, 1 of them a synthesis that pooled it.
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Who cites it
5 citing papers in PubMed, 1 synthesis or guideline pooled it.
- Reproductive life stages and cognitive outcomes: a systematic review in Latin American and Caribbean women.Frontiers in aging neuroscience · 2026Pooled it
- Ocular microvascular changes in hypoestrogenism: an OCT/OCTA systematic review and meta-analysis.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026Review
- Vitamin D Status and Reproductive Hormonal Profiles in Early Versus Physiological Menopause: A Comparative Observational Study.Biomedicines · 2026Article
- Lifetime Exposure to Endogenous Estradiol and Markers of Dementia Risk: Associations with Later Life Cognitive, Behavioral, and Functional Complaints.Diagnostics (Basel, Switzerland) · 2026Article
- Association between reproductive history and menopausal timing: exploring rural-urban differences in a cross-sectional survey.BMC women's health · 2026Article
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Authors and funding
4 authors.
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Abstract
This study aimed to examine trends in the ages of menarche and menopause, and related factors, among women in the Fasa Cohort Study. We analyzed cross-sectional data from the Fasa cohort, part of the Persian cohort study, which included 11,000 Iranian adults aged 35 to 75, with 5311 being women. These women were categorized into four age groups: 35-44, 45-54, 55-64, and 65-75 years. We explored changes in mean ages at menarche and menopause, along with associated factors, using SPSS 22 software and applying descriptive statistics, chi-square tests, t-tests, ANOVA, and multivariable linear regression. Results indicated a reduction in mean age at menarche from 14.16 to 13.40 years and a decline in mean age at menopause from 52.27 to 40.25 years across the same age groups, both statistically significant (p < 0.001). A significant relationship was found between age at menopause and factors such as education level, marital status, hypertension, and thyroid disease (p < 0.001). Women without a history of hypertension experienced menopause 0.84 years later than those with the condition, and those without thyroid disease had a delay of 0.75 years. Additionally, each year a woman delays having her first child corresponds to a 0.11-year increase in her age at menopause.
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