ArticleEuropean journal of pediatrics2025
Letter to the editor: heterogeneity in effects of PDA treatment.
Article in European journal of pediatrics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Abstract
The recent meta-analysis by Matsushita et al on "Heterogeneity in treatment response for patent ductus arteriosus" confirms prior results showing that medical treatment of PDA does not reduce but increases mortality. The discussion implies that there is heterogeneity in effects of treatment on mortality, but this is not consistent with the data. The implication of their analysis is that early medical treatment of PDA in preterm infants should be abandoned, as recommended in the recent Clinical Report from the American Academy of Pediatrics.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.