Evidence map›Paper›PMID 40419668›Full record

ArticleScientific reports2025

Physical and inflammatory aspects associated to respiratory sarcopenia in community-dwelling older women.

Leonardo Augusto da Costa Teixeira, Alessandra de Carvalho Bastone, Luana Aparecida Soares, Maria Fernanda Dos Santos Mourão, Juliana Nogueira Pontes Nobre, Ângela Alves Viegas, Adriana Netto Parentoni, Pedro Henrique Scheidt Figueiredo, Redha Taiar, Vanessa Amaral Mendonça and 1 more

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Scientific reports, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

11 authors.

Leonardo Augusto da Costa TeixeiraPostgraduate Program in Health Sciences, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100-000 , Diamantina, Minas Gerais, Brazil. leonardo.augusto@ufvjm.edu.br.
Alessandra de Carvalho BastonePostgraduate Program in Rehabilitation and Functional Performance, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100- 000, Diamantina, Minas Gerais, Brazil.
Luana Aparecida SoaresPostgraduate Program in Rehabilitation and Functional Performance, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100- 000, Diamantina, Minas Gerais, Brazil.
Maria Fernanda Dos Santos MourãoDepartment of Physiotherapy, Federal University of Vales do Jequitinhonha and Mucuri, MGT Highway 367 - Km 583, nº 5000, 39.100-000, Diamantina, Minas Gerais, Brazil.
Juliana Nogueira Pontes NobrePostgraduate Program in Health Sciences, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100-000 , Diamantina, Minas Gerais, Brazil.
Ângela Alves ViegasPostgraduate Program in Health Sciences, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100-000 , Diamantina, Minas Gerais, Brazil.
Adriana Netto ParentoniDepartment of Physiotherapy, Federal University of Vales do Jequitinhonha and Mucuri, MGT Highway 367 - Km 583, nº 5000, 39.100-000, Diamantina, Minas Gerais, Brazil.
Pedro Henrique Scheidt FigueiredoPostgraduate Program in Health Sciences, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100-000 , Diamantina, Minas Gerais, Brazil.
Redha TaiarMaterials and Mechanical Engineering (MATIM), University of Reims Champagne Ardenne, Reims, 51100, France.
Vanessa Amaral MendonçaPostgraduate Program in Health Sciences, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100-000 , Diamantina, Minas Gerais, Brazil.
Ana Cristina Rodrigues LacerdaPostgraduate Program in Health Sciences, Federal University of Vales do Jequitinhonha and Mucuri (UFVJM), MGT Highway 367 - Km 583, nº 5000, 39.100-000 , Diamantina, Minas Gerais, Brazil. lacerda.acr@ufvjm.edu.br.

Funding

Conselho Nacional de Desenvolvimento Científico e Tecnológico CNPq-402574/2021-4 and CNPq-151412/2024-3Coordenação de Aperfeiçoamento de Pessoal de Nível Superior PROEXT-PG 88881.926996/2023-01Fundação de Amparo à Pesquisa do Estado de Minas Gerais APQ-00277-24, APQ-04955-23, APQ-01328-18
6 · The paper itself

Abstract

To investigate the relationship between respiratory sarcopenia with physical tests and a set of inflammatory biomarkers, seventy-one older women from the community with age 75 ± 7 years and BMI 26 ± 4 kg/m² were evaluated for appendicular lean mass using Dual X-ray Absorptiometry, respiratory muscle strength using an analog manuvacuometer, physical tests using handgrip strength, timed up and go and sit to stand in chair tests, and a panel of inflammatory biomarkers was measured, containing Adiponectin, BNDF, IFN, IL-2, IL-4, IL-5, IL-6, IL-8, IL-10, Leptin, Resistin, TNF and their soluble receptors sTNFr-1 and sTNFr-2. The analyzes suggest that older women with respiratory sarcopenia also had significantly low physical function and higher concentrations of sTNFr-2 (> 2241pg/ml), additionally respiratory muscle strength was inversely associated with sTNFr-2 concentrations (MIP: β = -0.48; R² = 0.24; p < 0.001; MEP: β = -0.35; R² = 0.12; p = 0.003). These results contribute to the discussion about the pathophysiology and to the strategies for diagnosing and monitoring respiratory sarcopenia in community-dwelling older women.

Indexed as

InflammationRespiratory MusclesSarcopeniaAbsorptiometry, PhotonAgedAged, 80 and overBiomarkersCytokinesFemaleHand StrengthHumansIndependent LivingMuscle StrengthBiomarkersCytokinesDiagnosisInflammationPhysical performanceRespiratory sarcopeniaSGD3-10sTNFr-2

Identifiers

PMID40419668
PMCPMC12106602

What OpenQuestion holds

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LicenceCC BY-NC-ND
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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.