ArticleScientific data2025
The Dallas Lifespan Brain Study: A Comprehensive Adult Lifespan Data Set of Brain and Cognitive Aging.
Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 16 papers.
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Who cites it
16 citing papers in PubMed.
- Hybrid CNN-Transformer Framework for Molecular Imaging-based Early Alzheimer's Disease Detection.Molecular imaging and biology · 2026Article
- Resting-state brain age is associated with cognitive and sensorimotor abnormalities in schizophrenia spectrum disorders: a validation & longitudinal study.Translational psychiatry · 2026Article
- Evaluating the 8-Year Association Between Cognition and Beta Amyloid in the Dallas Lifespan Brain Study Cohort.Brain and behavior · 2026Article
- Multimodal MRI prediction of cognitive functioning across the lifespan: separating between-person differences from within-person changes.GeroScience · 2026Article
- A longitudinal resource for mapping interindividual variation in the aging connectome.Scientific data · 2026Article
- TRAECR: A Tool for Preprocessing Positron Emission Tomography Imaging for Statistical Modeling.ArXiv · 2026Article
- Deep Computational Anatomy via Latent-Aligned Multiview Normalizing Flows.bioRxiv : the preprint server for biology · 2026Article
- Predicting categorical and continuous Alzheimer's disease outcomes from a single MRI scan.Nature aging · 2026Article
- Resting-State Brain Age Predicts Cognitive and Sensorimotor Deficits in Schizophrenia Spectrum Disorders: A Validation & Longitudinal Study.Research square · 2026Article
- Radon-Guided Wavelet-Domain Attention U-Net for Periodic Artifact Suppression in Brain MRI.Journal of imaging · 2026Article
- Differential tractography suggests a "left-to-whole" white matter degeneration pattern in aging.Brain imaging and behavior · 2026Article
- Enhancing brain age estimation with structural MRI and synthesized cerebral blood volume maps.Brain communications · 2026Article
- Systematic fMRI signal differences across cohorts alter lifespan trajectories of functional brain networks.Imaging neuroscience (Cambridge, Mass.) · 2026Article
- An open, longitudinal resource for mapping interindividual variation in the aging connectome.medRxiv : the preprint server for health sciences · 2025Article
- Article
- Non-invasive MRI of choroid plexus vascular function.Imaging neuroscience (Cambridge, Mass.)Article
Corrections and comments
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Authors and funding
16 authors.
Funding
Abstract
The Dallas Lifespan Brain Study (DLBS) was designed to integrate brain and cognition across the adult lifespan. Participants (n = 464) were between age 21 and 89 years at time of first assessment and returned approximately every 3.5-5 years for a second (n = 338) and third epoch (n = 224) of data collection. The three epochs included a comprehensive neuropsychological battery, questionnaires that assessed physical health, psychosocial status, and brain health, structural MRI scans (including T1-weighted imaging and diffusion-weighted imaging), a hypercapnia scan, an arterial spin labeling scan, and four functional fMRI scans. Additionally, measures of amyloid and tau were collected with AV-45 (Florbetapir) and AV-1451 (Flortaucipir). Key innovations were robust sampling of middle-aged participants and inclusion of PET data for amyloid and tau in a cognitively normal sample. This large data set has recently been published on OpenNeuro.org open-access and provides the opportunity for researchers to test many hypotheses about brain and cognition across human adulthood, including longitudinal hypotheses, with these data across a multi-year span.
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Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.