Evidence map›Paper›PMID 40419543›Full record

ArticleScientific data2025

Transcriptomics and metabolomics profiling of Paris polyphylla var. yunnanensis with different growth years.

Xiaoye Zhang, Jia Chen, Ping Xu, Xuan Zhang, Shuiyi Yang, Jie Zhang, Xiheng Wan, Yingsi Gao, Guowei Zheng

Abstract readDataset
In one paragraph

Article in Scientific data, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Article
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4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Xiaoye Zhang *Yunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming, 650500, P.R. China.
Jia Chen *Yunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming, 650500, P.R. China.
Ping XuCollege of Chinese Material Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, P.R. China.
Xuan ZhangCollege of Chinese Material Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, P.R. China.
Shuiyi YangCollege of Chinese Material Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, P.R. China.
Jie ZhangCollege of Chinese Material Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, P.R. China.
Xiheng WanCollege of Chinese Material Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, P.R. China.
Yingsi GaoCollege of Chinese Material Medicine, Yunnan University of Traditional Chinese Medicine, Kunming, 650500, P.R. China.
Guowei ZhengYunnan Key Laboratory of Dai and Yi Medicines, Yunnan University of Chinese Medicine, Kunming, 650500, P.R. China. gwzhengkm@163.com.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Paris polyphylla var. yunnanensis is a widely cultivated rhizomatous perennial woody plant known for producing highly valued steroidal saponins. Steroidal saponins serve as the primary active components and exhibit a variety of pharmacological effects. Their production is closely correlated with the growth environment and developmental stages of P. polyphylla. However, the medicinal value of P. polyphylla cultivated for varying durations remains unclear. In this study, we collected samples of P. polyphylla aged 3 to 8 years for metabolome and transcriptome sequencing analysis. The total saponin content was found to be significantly higher in 8-year-old P. polyphylla compared to younger plants. A total of 1,510 metabolites and 270.65 Gb of clean data were identified from these samples. This study provides insights into the medicinal values of P. polyphylla at different growth stages and elucidates the metabolic pathways for specific steroidal saponins.

Indexed as

MelanthiaceaeMetabolomeTranscriptomeGene Expression ProfilingMetabolomicsSaponinsSaponins

Identifiers

PMID40419543
PMCPMC12106840

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.