Evidence map›Paper›PMID 40419458›Full record

ArticleJournal of medicinal chemistry2025

Regio- and Stereoselective Synthesis of Nitro-fatty Acids as NRF2 Pathway Activators Working under Ambient or Hypoxic Conditions.

Daniel Chrenko, Jana Pereckova, Martina Zatloukalová, Jan Vacek, Jiří Pospíšil, Tomas Perecko

Abstract read
In one paragraph

Article in Journal of medicinal chemistry, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

0numbers the graph read from it
0cells of the map it votes in
0citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

0 citing papers in PubMed.

No citing paper in PubMed yet.

4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Daniel ChrenkoDepartment of Chemical Biology, Faculty of Science, Palacky University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0002-5926-5324
Jana PereckovaDepartment of Cell Biology and Radiobiology, Institute of Biophysics of the Czech Academy of Sciences, Kralovopolska 135, 612 00 Brno, Czech Republic.ORCID 0000-0002-7565-993X
Martina ZatloukalováDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, 775 15 Olomouc, Czech Republic.
Jan VacekDepartment of Medical Chemistry and Biochemistry, Faculty of Medicine and Dentistry, Palacky University, Hnevotinska 3, 775 15 Olomouc, Czech Republic.ORCID 0000-0001-5490-082X
Jiří PospíšilDepartment of Chemical Biology, Faculty of Science, Palacky University, Šlechtitelů 27, CZ-783 71 Olomouc, Czech Republic.ORCID 0000-0002-0198-8116
Tomas PereckoDepartment of Cell Biology and Radiobiology, Institute of Biophysics of the Czech Academy of Sciences, Kralovopolska 135, 612 00 Brno, Czech Republic.ORCID 0000-0003-4278-4088

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

Nitro-fatty acids (NO

Indexed as

Fatty AcidsNF-E2-Related Factor 2Nitro CompoundsAnimalsCell HypoxiaHeme Oxygenase-1Linoleic AcidsMiceOxygenSignal TransductionStereoisomerismFatty AcidsHeme Oxygenase-1Linoleic AcidsNfe2l2 protein, mouseNF-E2-Related Factor 2Nitro CompoundsOxygen

Identifiers

PMID40419458
PMCPMC12169669

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.