Evidence map›Paper›PMID 40419173›Full record

ArticleMagnetic resonance imaging2025

MATI: A GPU-accelerated toolbox for microstructural diffusion MRI simulation and data fitting with a graphical user interface.

Junzhong Xu, Sean P Devan, Diwei Shi, Adithya Pamulaparthi, Nicholas Yan, Zhongliang Zu, David S Smith, Kevin D Harkins, John C Gore, Xiaoyu Jiang

Abstract read
In one paragraph

Article in Magnetic resonance imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 9 papers.

0numbers the graph read from it
0cells of the map it votes in
9citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

9 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
  4. Observational
  5. Article
  6. Article
  7. Article
  8. Article
  9. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

10 authors.

Junzhong XuVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States of America; Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, United States of America. Electronic address: junzhong.xu@vanderbilt.edu.
Sean P DevanVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America.
Diwei ShiTsinghua University, Beijing, China.
Adithya PamulaparthiDepartment of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, United States of America.
Nicholas YanFarragut High School, Knoxville, TN, United States of America.
Zhongliang ZuVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America.
David S SmithVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, United States of America; Department of Electrical and Computer Engineering, Vanderbilt University, Nashville, TN, United States of America.
Kevin D HarkinsVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America.
John C GoreVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Biomedical Engineering, Vanderbilt University, Nashville, TN, United States of America; Department of Physics and Astronomy, Vanderbilt University, Nashville, TN, United States of America.
Xiaoyu JiangVanderbilt University Institute of Imaging Science, Vanderbilt University Medical Center, Nashville, TN, United States of America; Department of Radiology and Radiological Sciences, Vanderbilt University Medical Center, Nashville, TN, United States of America.

Funding

Tumor Immunology and Microenvironment Research ProgramP30CA068485 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Ben Ho Park · 1995 to 2026
$172.8M
Overall: Eunice Kennedy Shriver Intellectual and Developmental Disabilities Research Center at VanderbiltP50HD103537 · NICHD · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Jeffrey L Neul · 2020 to 2026
$10.3M
MRI of tumor-infiltrating lymphocytes using MRI-cytometryR01CA269620 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI XU, JUNZHONG · 2022 to 2025
$2.3M
Evaluating Advanced Diffusion of the Human Spinal Cord: Application to MSR01NS117816 · NINDS · VANDERBILT UNIVERSITY MEDICAL CENTER · PI SMITH, SETH A · 2021 to 2025
$1.8M
Uncovering the time dependent diffusion coefficient in neural tissue with MRIR01EB031954 · NIBIB · VANDERBILT UNIVERSITY MEDICAL CENTER · PI HARKINS, KEVIN D · 2021 to 2024
$1.5M
in vivo MR characterization of pathological changes in liver microstructuresR01DK135950 · NIDDK · VANDERBILT UNIVERSITY MEDICAL CENTER · PI Xiaoyu Jiang · 2024 to 2026
$1.2M
Differentiation of tumor progression from radiation necrosis using MR cell size imagingR21CA270731 · NCI · VANDERBILT UNIVERSITY MEDICAL CENTER · PI XU, JUNZHONG · 2023 to 2024
$440k
NCI NIH HHS P30 CA068485NCI NIH HHS R01 CA269620NCI NIH HHS R21 CA270731NIBIB NIH HHS R01 EB031954NICHD NIH HHS P50 HD103537NIDDK NIH HHS R01 DK135950NINDS NIH HHS R01 NS117816
6 · The paper itself

Abstract

purposeTo introduce MATI (Microstructural Analysis Toolbox for Imaging), a versatile MATLAB-based toolbox that combines both simulation and data fitting capabilities for microstructural dMRI research.

methodsMATI provides a user-friendly, graphical user interface that enables researchers, including those without much programming experience, to perform advanced simulations and data analyses for microstructural MRI research. For simulation, MATI supports arbitrary microstructural tissues and pulse sequences. For data fitting, MATI supports a range of fitting methods, including traditional non-linear least squares, Bayesian approaches, machine learning, and dictionary matching methods, allowing users to tailor analyses based on specific research needs.

resultsOptimized with vectorized matrix operations and high-performance numerical libraries, MATI achieves high computational efficiency, enabling rapid simulations and data fitting on CPU and GPU hardware. While designed for microstructural dMRI, MATI's generalized framework can be extended to other imaging methods, making it a flexible and scalable tool for quantitative MRI research.

conclusionMATI offers a significant step toward translating advanced microstructural MRI techniques into clinical applications.

Indexed as

Diffusion Magnetic Resonance ImagingImage Processing, Computer-AssistedSoftwareUser-Computer InterfaceAlgorithmsBayes TheoremBrainComputer GraphicsComputer SimulationHumansLeast-Squares AnalysisMachine LearningDiffusionMagnetic resonance imagingOscillating gradient

Identifiers

PMID40419173
PMCPMC12805661

What OpenQuestion holds

Textmetadata
LicenceTDM
Read underepoch 390

Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.