ArticleJMIR infodemiology2025
Tracking Public Interest in Rare Diseases and Eosinophilic Disorders in Germany: Web Search Analysis.
Article in JMIR infodemiology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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3 authors.
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Abstract
Background: Eosinophilia and hypereosinophilic syndrome (HES) are rare disorders grouped under the term hypereosinophilic disorders. They are diagnosed based on an increased number of eosinophils. They can also cause serious symptoms, including skin, lung, and gastrointestinal problems. These disorders are very rarely recognized due to their rarity and misdiagnosis. Objective: This study analyzes public interest in hypereosinophilic disorders using data on internet search volume in Germany between 2020 and 2023. Objectives include identifying frequently searched terms, evaluating temporal trends, analyzing seasonal patterns, evaluating geographic differences in search behavior, and identifying unmet information needs and frequently searched risk factors. Methods: A retrospective analysis using Google Ads Keyword Planner gathered monthly search volume data for 12 German terms related to hypereosinophilic disorders. These terms were selected based on their medical relevance and common usage identified from medical literature. Data were analyzed descriptively, with trends, seasonal variations, and geographical distributions examined. Chi-square tests and correlation analysis assessed statistical significance. Results: A total of 178 keywords were identified, resulting in a search volume of 1,745,540 queries. The top keyword was "eosophile," a misspelling, followed by "eosinophilia" and "HES." The main categories included "Eosinophilia," "Eosinophils," and "Churg-Strauss syndrome." Temporal analysis showed seasonal growth in search volumes, peaking in January 2023, with higher interest during winter. Geographical analysis showed regional variations. Conclusions: This research shows a growing public interest in eosinophilic diseases, reflected by a steadily increasing search volume over time. This is particularly evident in searches for basic definitions and diagnostic criteria, such as "eosinophils" or "symptoms of eosinophilic diseases." This increase in search volume, which peaked in January 2023, indicates an increased interest in accurate and readily available information for rare conditions.
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