Trial reportJMIR human factors2025
A Web-Based Lifestyle-Related Course for People Living With Multiple Sclerosis: Quantitative Evaluation of Course Completion, Satisfaction, and Lifestyle Changes Among Participants Enrolled in a Randomized Controlled Trial.
Trial report in JMIR human factors, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
1 citing paper in PubMed.
- The Big Picture: 26 Years of Longitudinal Findings About Health Promotion and Quality of Life in Multiple Sclerosis.Healthcare (Basel, Switzerland) · 2026Review
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
7 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundWeb-based health courses providing lifestyle-related information can potentially increase knowledge, facilitate behavior change, and improve health outcomes for people living with multiple sclerosis (MS). Despite the low engagement with web-based programs by this population, few studies have evaluated factors influencing engagement. This study evaluated engagement with our 6-week lifestyle-related course (Multiple Sclerosis Online Course; MSOC) by participants enrolled in a large, international randomized controlled trial, as well as preliminary outcomes.
objectiveThis study aimed to quantitatively assess engagement with the MSOC (the intervention course [IC] and standard-care course [SCC]), motivators of and barriers to participants' course completion, course satisfaction, engagement with the community forum, and intentions to implement lifestyle changes.
methodsWe collected data via a baseline survey before course commencement and an evaluation survey 1 month after the 6-week course. Course completers were queried on motivators of completion, course satisfaction, previous knowledge, forum participation, and intentions to adopt lifestyle changes. Noncompleters were queried on barriers to course completion. Differences between the 2 study arms were examined using chi-square and 2-tailed t tests. Multivariable linear regression models assessed factors (sociodemographic and course and health related) associated with participants' intentions to adopt lifestyle changes adjusting for baseline lifestyle factors. Moderation analyses were conducted to test group differences.
resultsOf the 857 participants, 442 (51.6%) completed the MSOC (IC: n=218, 49.3%; SCC: n=224, 50.7%), and 291 (34%) completed the evaluation survey (n=254, 87.3% course completers; n=37, 12.7% noncompleters). Key motivators of course completion included an interest in participating in MS research, optimizing health, course flexibility, and relevant and useful course content. Barriers to course completion included time constraints and technical issues. Most course completers rated the MSOC as "excellent/very good" (IC: 92/126, 73%; SCC: 78/128, 60.9%; P=.17). Engagement with the facilitator-led community forum was higher in the IC than in the SCC (56/126, 44.4% vs 32/128, 25%; P=.003). More IC completers versus SCC completers expressed their intention to adopt dietary changes (89/125, 71.2% vs 74/127, 58.3%; P=.04), increase their sun exposure (82/124, 66.1% vs 62/124, 50%; P=.01), supplement with omega-3 (84/125, 67.2% vs 60/126, 47.6%; P=.004), and practice meditation (85/124, 68.5% vs 66/126, 52.4%; P=.009). Forum engagement, course satisfaction, new course content, and an interest in receiving additional course content were associated with intentions to adopt lifestyle changes across both study arms.
conclusionsThe web-based lifestyle IC provided new and satisfactory content and facilitated intentions to adopt lifestyle changes. Positive associations between engagement with the community forum and intentions to implement lifestyle changes and identifying barriers to completion such as time constraints provide important insights to inform the design of future digital health interventions for people living with MS and possibly other chronic conditions.
trial registrationAustralian New Zealand Clinical Trials Registry (ANZCTR) ACTRN12621001605886; https://www.anzctr.org.au/Trial/Registration/TrialReview.aspx?id=382778&isReview=true.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.