Evidence map›Paper›PMID 40418648›Full record

ArticlePlant biotechnology journal2025

TaPP2C-a6 interacts with TaDOG1Ls and regulates seed dormancy and germination in wheat.

Qian Zhang, Xiaofen Yu, Ruibin Wang, Ya'nan Wu, Fu Shi, Yufan Zhang, Hongyan Zhao, Huazhen Xu, Jiao Pan, Yuesheng Wang and 8 more

Abstract read
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In one paragraph

Article in Plant biotechnology journal, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.

0numbers the graph read from it
0cells of the map it votes in
3citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

3 citing papers in PubMed.

  1. Article
  2. Article
  3. Review
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

18 authors.

Qian ZhangThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Xiaofen YuKey Laboratory of Plant Germplasm Enhancement and Specialty Agriculture, Wuhan Botanical Garden, Innovative Academy of Seed Design, Chinese Academy of Sciences, Wuhan, China.
Ruibin WangThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Ya'nan WuThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Fu ShiThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Yufan ZhangThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Hongyan ZhaoThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Huazhen XuThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Jiao PanThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Yuesheng WangThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Min TuHubei Technical Engineering Research Center for Chemical Utilization and Engineering Development of Agricultural and Byproduct Resources, School of Chemical and Environmental Engineering, Wuhan Polytechnic University, Wuhan, China.
Junli ChangThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Zhanwang ZhuInstitute of Food Crops, Hubei Academy of Agricultural Sciences, Wuhan, China.
Guangyuan HeThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0002-1633-465X
Mingjie ChenThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Ling ChenInstitute of Food Crops, Hubei Academy of Agricultural Sciences, Wuhan, China.
Guangxiao YangThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.
Yin LiThe Genetic Engineering International Cooperation Base of Chinese Ministry of Science and Technology, Key Laboratory of Molecular Biophysics of Chinese Ministry of Education, College of Life Science and Technology, Huazhong University of Science and Technology, Wuhan, China.ORCID https://orcid.org/0000-0002-5454-4201

Funding

"Double First-Class" Initiative HUST Research Institution Supporting ProjectEarmarked Fund for China Agriculture Research System CARS-03Fundamental Research Funds for Central Universities, HUST 2021XXJS070Fundamental Research Funds for Central Universities, HUST 3004170157Hubei Provincial Key Research and Development Project 2022BBA0035National Genetically Modified New Varieties of Major Projects of China 2016ZX08010004-004National Natural Science Foundation of China 31371614National Natural Science Foundation of China 31771418National Natural Science Foundation of China 32272126National Natural Science Foundation of Hubei China 2016CFB549Opening Fund of Hubei Key Laboratory of Bioinorganic Chemistry & Materia Medica BCMM202205Opening Fund of Key Laboratory of Forage and Endemic Crop Biology, Ministry of Education FECBOF2021002The Start-Up Research Funding of Wuhan Polytechnic University 2021RZ100The Start-Up Research Funding of Wuhan Polytechnic University 53210052172
6 · The paper itself

Abstract

Modern wheat cultivation requires seed to germinate rapidly and uniformly with weak dormancy. However, such varieties tend to undergo pre-harvest sprouting (PHS) if the harvest overlaps with the rainy season, causing substantial yield losses. Knowledge regarding the mechanisms of seed dormancy in wheat (Triticum aestivum L.) is limited, with only a few causal genes of the many PHS quantitative trait loci (QTLs) characterized. Here, we emphasize the involvement of ABA signalling core components in regulating seed dormancy and germination in wheat. TaPP2C-a6 was identified as the likely causal gene of wheat PHS-QTLs QPhs.wsu-1A/1B and QPhs1D.1_nwafu loci. Both TaPP2C-a6 and TaPP2C-a7 were highly expressed at embryonic developmental stages and germinating seeds, whereas TaPP2C-a6 was up-regulated during embryo maturation and seed germination. TaPP2C-a6 and TaPP2C-a7 were clade-A PP2Cs that interacted with TaPYLs and class III TaSnRK2s; however, TaPP2C-a6 showed stronger interactions with TaDOG1L members than those of TaPP2C-a7. TaPP2C-a6 overexpression in transgenic Arabidopsis thaliana caused a more severe reduction in ABA sensitivity than TaPP2C-a7 overexpression. Overexpression of TaPP2C-a6 in transgenic A. thaliana and wheat increased PHS levels, whereas TaPP2C-a7 transgenic A. thaliana did not affect PHS levels, confirming that TaPP2C-a6 is a novel regulator of wheat seed dormancy and germination. In summary, we demonstrated that leveraging the knowledge of seed dormancy and germination from model species could rapidly identify the causal genes of PHS-QTLs in wheat. Significantly, we showed that the TaPP2C-TaDOG1L interactions, particularly the interaction strength, could be a new aspect in the regulation of seed dormancy and germination.

Indexed as

GerminationPlant DormancyPlant ProteinsSeedsTriticumAbscisic AcidGene Expression Regulation, PlantQuantitative Trait LociAbscisic AcidPlant ProteinsABA signallingclade‐A PP2CsDOG1pre‐harvest sproutingseed dormancywheat

Identifiers

PMID40418648
PMCPMC12310832

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.