Evidence map›Paper›PMID 40418490›Full record

ArticleJapanese journal of ophthalmology2025

Descemet membrane endothelial keratoplasty after cataract surgery with presbyopia-correcting intraocular lens for coexisting Fuchs endothelial corneal dystrophy and cataract.

Hideaki Yokogawa, Takahiko Hayashi, Akira Kobayashi, Natsuko Mori, Kenichiro Yamazaki, Hirohito Ohta, Masato Takeda, Ami Igarashi, Satoru Yamagami

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Article in Japanese journal of ophthalmology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.

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1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

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3 · Its place in the literature

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No citing paper in PubMed yet.

4 · The record

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5 · Who and what money

Authors and funding

9 authors.

Hideaki YokogawaDepartment of Ophthalmology, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa-shi, Ishikawa-ken, 920-8641, Japan. hyoko@med.kanazawa-u.ac.jp.
Takahiko HayashiDepartment of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
Akira KobayashiDepartment of Ophthalmology, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa-shi, Ishikawa-ken, 920-8641, Japan.
Natsuko MoriDepartment of Ophthalmology, Kanazawa University Hospital, 13-1 Takara-machi, Kanazawa-shi, Ishikawa-ken, 920-8641, Japan.
Kenichiro YamazakiOmiya Nanasato Eye Institute, Saitama, Japan.
Hirohito OhtaShimono-jo Eye Clinic, Takasaki, Gunma, Japan.
Masato TakedaDepartment of Ophthalmology, Yokohama Minami Kyosai Hospital, Kanagawa, Japan.
Ami IgarashiDepartment of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Itabashi, Tokyo, Japan.
Satoru YamagamiDepartment of Ophthalmology, Department of Visual Sciences, Nihon University School of Medicine, Itabashi, Tokyo, Japan.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

purposeTo assess the outcomes of Descemet membrane endothelial keratoplasty (DMEK) staged after implantation of presbyopia-correcting intraocular lenses (IOLs) in patients with coexisting Fuchs endothelial corneal dystrophy (FECD) and cataract. STUDY

designRetrospective, interventional case series

methodsWe enrolled six eyes of three patients with coexisting FECD and cataract (3 women, age 67.8 ± 6.5 years) treated with presbyopia-correcting IOL implantation, followed by DMEK. The modified Krachmer grade, visual outcomes, and incidence of intra- and postoperative complications were analyzed.

resultsModified Krachmer FECD grades 4, 5, and 6 were observed in one, two, and three eyes, respectively. The mean best-corrected visual acuity (BCVA) was dissatisfactory with the primary presbyopia-correcting IOL (decimal 0.45), it improved significantly (decimal 1.0, P = 0.027) after DMEK and all eyes acquired satisfactory uncorrected distance and near (30 cm) vision (mean, decimal, distance 0.85 and near 0.56). The manifest spherical equivalent after DMEK was within the acceptable range (-0.375 D to 0.0 D). Rebubbling was required in four eyes, but no instances of other postoperative complications or primary graft failure were encountered.

conclusionDMEK staged after implantation of presbyopia-correcting IOLs is a viable option for patients with coexisting FECD and cataract.

Indexed as

CataractCataract ExtractionDescemet Stripping Endothelial KeratoplastyFuchs' Endothelial DystrophyLenses, IntraocularLens Implantation, IntraocularPresbyopiaAgedFemaleFollow-Up StudiesHumansMaleMiddle AgedPostoperative ComplicationsRefraction, OcularRetrospective StudiesCorneal transplantationDescemet membrane endothelial keratoplastyFuchs endothelial corneal dystrophyPresbyopia-correcting intraocular lens

Identifiers

PMID40418490

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.