ArticleMethods in molecular biology (Clifton, N.J.)2025
Quantitative Measurement of 8-Hydroxy-2'-Deoxyguanosine in Serum/Plasma and Urine Using an Enzyme-Linked Immunosorbent Assay.
Article in Methods in molecular biology (Clifton, N.J.), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
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Who cites it
1 citing paper in PubMed.
- Comparison of the effects of clear aligners and fixed appliances on the oral microbiota and reactive oxygen species: a prospective study.Frontiers in cellular and infection microbiology · 2025Article
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Abstract
8-Hydroxy-2-deoxyguanosine (8-OHdG), generated as a result of reactive oxygen species (ROS)-mediated DNA damage repair, is the most widely recognized biomarker of oxidative damage to DNA, since guanosine is the most oxidized nucleobase in DNA. As a crucial marker of oxidative DNA damage, 8-OHdG has potential for assessing severity and prognosis in diseases and has been associated with a variety of pathologies, including chronic kidney disease, heart failure, and various cancers. This chapter focuses on the measurement of 8-OHdG concentrations as a key biomarker of oxidative stress. Although high-performance liquid chromatography (HPLC) has conventionally been used for the measurement of 8-OHdG concentrations, enzyme-linked immunosorbent assays (ELISA) have become increasingly widespread. This chapter presents a detailed protocol for the measurement of 8-OHdG concentrations using a highly sensitive ELISA kit suitable for serum/plasma and urine.
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