SynthesisJournal of assisted reproduction and genetics2025
Prevalence of psychological problems among individuals and couples during assisted reproductive technology(ART) treatment: a systematic review and meta-analysis.
Synthesis in Journal of assisted reproduction and genetics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.
What it found
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The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
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Who cites it
5 citing papers in PubMed.
- Stratified Psychosocial Care in Assisted Reproductive Technologies: A Narrative Review and Conceptual Framework Across the IVF Pathway.Journal of clinical medicine · 2026Review
- Sex-specific associations between psychological resilience and blastocyst quality.Reproduction & fertility · 2026Observational
- Psychosocial outcomes of reproductive genetic carrier screening up to five years post-result.European journal of human genetics : EJHG · 2026Article
- The Lived Experience of Couples Undergoing In Vitro Fertilisation in Greece: An Interpretative Phenomenological Analysis.Healthcare (Basel, Switzerland) · 2026Article
- Mapping the symptom network of anxiety, depression, somatic symptoms and sleep disturbances in 15,642 infertile women: a retrospective cohort study identifying targets for fertility care.Frontiers in public health · 2026Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
Abstract
backgroundThe psychological problems of infertile couples deserve more attention given the impact on pregnancy outcomes.
aimsThis systematic review and meta-analysis was designed to assess the prevalence of anxiety, depression, and stress in couples during assisted reproductive treatment. MATERIALS AND
methodsWe conducted searches on PubMed, Embase, and Web of Science from the outset until September 2024. Random-effects models were conducted to estimate the pooled prevalence of anxiety, depression and stress. Subgroup analyses were performed to seek potential sources of heterogeneity. The Egger's test was utilized to assess publication bias.
resultsThe meta-analysis included 40 studies involving 16,042 participants. The pooled prevalence of anxiety, depression and stress symptoms in infertile women were 48.0% (95%CI 36.6%-59.9%), 35.6% (95%CI 28.0%-43.3%) and 52.2% (95%CI 13.2-91.1%) respectively, while those in infertile men were 28.4% (95%CI 15.4%-43.4%) , 18.6% (95%CI 13.4%-23.8%) and 47.2% (95%CI 16.1%-78.4%) respectively. Subgroup analysis revealed the differences in country economic level, continent, assessment instrument and sample size.
conclusionsMany couples experienced anxiety, depression and stress symptoms during assisted reproductive therapy. It is important for healthcare professionals to develop and implement effective strategies for the prevention and intervention of psychological issues.
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