ArticleEJNMMI physics2025
Performance evaluation of a medium axial field-of-view sparse PET system based on flat panels of monolithic LYSO detectors: a simulation study.
Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
4 citing papers in PubMed.
- Realization of long axial field-of-view PET technology in the clinic and research environment.The British journal of radiology · 2026Review
- Filling of incomplete sinograms from sparse PET detector configurations using a residual U-Net.Medical physics · 2026Article
- Instrumentation Digital Twins in PET and SPECT Imaging: Current Status, Challenges, and Future Directions.Computational and structural biotechnology journal · 2026Review
- Motion study on upright patient positioning in walk-through PET: evaluation in a clinical setting.EJNMMI physics · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
6 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundThe combination of longer axial field-of-view (AFOV) and time-of-flight positron emission tomography (PET) has significantly improved system sensitivity and, as a result, image quality. This study investigates a cost-effective extended AFOV PET system design using monolithic LYSO detectors with depth-of-interaction capabilities. These detectors, arranged in a vertical flat-panel geometry and positioned closer to the patient, enable superior spatial resolution while maintaining a compact and affordable system design. We simulate the performance of two flat-panel PET configurations: one with a fully populated 106 cm AFOV and another cost-efficient design featuring a reduced AFOV with axial gaps and vertical panel motion optimized for head and torso imaging.
methodsBoth configurations consist of two monolithic LYSO-based flat panels placed 50 cm apart. The panels are 71 cm wide, with the Long Flat Panel (L-FP) design extending to a length of 106 cm while the Sparse Medium Flat Panel (SpM-FP) design measures 60 cm in length. Monte Carlo simulations evaluated the two designs using the NEMA protocol and additional tests for a more thorough assessment. Sensitivity, spatial resolution, axial noise variability, and image quality were analyzed, and an XCAT phantom at standard dose was used to demonstrate the achievable clinical image quality.
resultsThe SpM-FP showed 4-5 times lower sensitivity than the L-FP, requiring an acquisition time of 2-3 min to match the image quality achieved by the L-FP in 30 s. This finding is supported by the contrast-to-noise ratio of the image quality phantom and the standard deviation values obtained from the liver and lung regions of the XCAT phantom. Both configurations achieved uniform spatial resolution below 2 mm in the two directions parallel to the panels and an average of 3-3.5 mm in the direction towards the panels, with slight degradation observed away from the center of the AFOV. Additionally, the axial noise profile of the SpM-FP revealed minimal variability.
conclusionsThe SpM-FP design shows potential as a cost-effective system, combining the benefits of extended AFOV, superior spatial resolution and high patient throughput.
Indexed as
Identifiers
What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.