ArticleActa neurochirurgica2025
Investigation of the hyperperfusion phenomenon following carotid artery stenting using preoperative computed tomography perfusion imaging.
Article in Acta neurochirurgica, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeThis study aimed to identify the most effective parameters of computed tomography perfusion imaging (CTP) using the Bayesian estimation to predict hyperperfusion phenomenon (HPP) risk after carotid artery stenting (CAS).
methodsWe retrospectively analyzed 46 patients who underwent CAS with preoperative CTP and preoperative and postoperative
resultsHPP occurred in four patients, with one developing cerebral hemorrhage. Significant differences were observed between the HPP and non-HPP groups in CBV (p = 0.001), MTT (p = 0.003), and TTP ratio (p = 0.011), and preoperative AI (p = 0.021). Among the CTP parameters and preoperative AI, the CBV ratio showed a positive correlation with the postoperative AI (r = 0.63, p < 0.01). The CBV ratio demonstrated the highest area under the curve (AUC) for predicting HPP (AUC = 0.95). However, after Benjamini-Hochberg correction, statistical significance was lost (adjusted p = 0.07).
conclusionThis study evaluated the predictive value of preoperative CTP using the Bayesian estimation method for identifying HPP risk after CAS. CBV ratio may serve as a potential parameter for predicting HPP.
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