SynthesisWorld journal of urology2025
Comparison of success rates between urethroplasty and perineal urethrostomy in the treatment of complex urethral strictures: a meta-analysis.
Synthesis in World journal of urology, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
0 citing papers in PubMed.
No citing paper in PubMed yet.
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
5 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
purposeThis study aimed to compare the effectiveness of urethroplasty and perineal urethrostomy (PU) in treating complex urethral strictures (CUS). CUS refers to strictures longer than 6 cm or those caused by prior surgeries, such as hypospadias or lichen sclerosus.
methodsA systematic literature search was conducted to identify relevant studies comparing urethroplasty and PU. The studies included were cohort designs that reported surgical success rates for both procedures. A total of 6 studies were included, involving 880 patients (624 undergoing urethroplasty and 256 undergoing PU). Data analysis was performed using Review Manager 5.3 software, and heterogeneity between studies was assessed using chi-square test (Cochran's Q) and the inconsistency index (I²).
resultsThe pooled analysis indicated no significant difference in the surgical success rates between the two groups (relative risk = 0.93, 95% CI: 0.84-1.03; p = 0.15). However, significant heterogeneity was observed (I² = 69%, p = 0.006), suggesting variability in the results across studies.
conclusionOur study shows that PU and urethroplasty have similar success rates in treating CUS. Given the quality of the studies and the identified limitations, it is not possible to draw definitive conclusions. Meanwhile, the management of CUS, especially those involving lichen sclerosus or failed hypospadias repair, should be carried out in referral centers with specialized expertise to optimize patient outcomes.
Indexed as
Identifiers
40418378What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.