Evidence map›Paper›PMID 40418333›Full record

ArticleEuropean journal of nuclear medicine and molecular imaging2025

Texture analysis and metabolic parameters of

Ayşenur Sinem Kartal, Mehmet Oğuz Kartal, Nadide Başak Gülleroğlu, Neriman Sarı, İnci Ergürhan İlhan, Nedim C M Gülaldı

Abstract read
In one paragraph

Article in European journal of nuclear medicine and molecular imaging, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 1 paper.

0numbers the graph read from it
0cells of the map it votes in
1citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

1 citing paper in PubMed.

  1. The predictive value ofFrontiers in medicine · 2026
    Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

6 authors.

Ayşenur Sinem KartalUniversity of Health Sciences, Department of Nuclear Medicine, Ankara Bilkent City Hospital, Ankara, Türkiye. asinemerdogan@hotmail.com.ORCID 0000-0003-1745-6672
Mehmet Oğuz KartalUniversity of Health Sciences, Department of Nuclear Medicine, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0009-0009-6440-4219
Nadide Başak GülleroğluUniversity of Health Sciences, Department of Pediatric Radiology, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0002-8533-3781
Neriman SarıUniversity of Health Sciences, Department of Pediatric Hematology-Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0001-5723-1385
İnci Ergürhan İlhanUniversity of Health Sciences, Department of Pediatric Hematology-Oncology, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0001-6114-3134
Nedim C M GülaldıUniversity of Health Sciences, Department of Nuclear Medicine, Ankara Bilkent City Hospital, Ankara, Türkiye.ORCID 0000-0003-1478-5294

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionWe aimed to investigate the value of primary tumour F-18 fluorodeoxyglucose ( MATERIALS AND

methodsTwenty-eight paediatric patients with STS who underwent

resultsIn univariate analysis SUVmax > 13.0 (p = 0.009), SUVpeak > 12.7 (p = 0.017), Histogram Entropy > 0.97 (p = 0.036), and NGTDM Busyness < 0.37 (p = 0.005) were associated with tumour response for the median follow-up of 25 months. NGTDM Busyness was an independent predictor for the treatment response (OR: 30.5; 95% CI: 1.50-618.5; p = 0.026). Age was associated with progression (Cut-off: 11 years, [AUC:0.73 (95% CI: 0,53 - 0,93)] 𝑝=0.022). Progression-free survival outcomes were assessed in aged > 11 years subpopulation. PFS was significantly shorter in patients with high GLSZM_GLNU (p = 0,024), GLSZM_ZSNU (p = 0,003), and TLG (p = 0,016). In multivariate analysis GLSZM_ZSNU > 13,04 (HR: 11.61; 95% CI: 1.35-54.02; p = 0.026) was an independent predictor of PFS in subpopulation aged > 11 years.

conclusionHeterogeneity texture features Histogram Entropy and NGTDM Busyness and metabolic PET parameters (SUV max and SUVpeak) can predict tumour response. In aged > 11 years patients subgroup analyses, GLSZM ZSNU was an independent factor for PFS.

Indexed as

Fluorodeoxyglucose F18Positron Emission Tomography Computed TomographySarcomaAdolescentChildChild, PreschoolFemaleHumansMalePrognosisRetrospective StudiesTreatment OutcomeFluorodeoxyglucose F18F-18 FDG PET/CTPaediatric oncologyPredictive valueSoft tissue sarcomaTexture analysis

Identifiers

PMID40418333
PMCPMC12589223

What OpenQuestion holds

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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.