Observational studyPediatric nephrology (Berlin, Germany)2025
Chronic kidney disease in Syrian children: a single center experience.
Observational study in Pediatric nephrology (Berlin, Germany), 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 3 papers.
What it found
Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.
The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.
The trial behind it
Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.
Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.
Who cites it
3 citing papers in PubMed.
- Clinical complications and anthropometric indicators of chronic kidney disease in a global context: scoping review.Pediatric nephrology (Berlin, Germany) · 2026Review
- Chronic Kidney Disease in Lithuanian Children: Single Center Experience.Acta medica Lituanica · 2026Article
- Delphi study on evidence-based CKD prevention strategies for nurses in resource-limited settings: focus on e-learning implementation.BMC nephrology · 2025Article
Corrections and comments
PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.
Authors and funding
2 authors.
Funding
No grant is acknowledged in the PubMed record.
Abstract
backgroundChronic kidney disease (CKD) is a condition marked by permanent kidney damage, which can eventually advance to kidney failure. Our study aimed to identify CKD causes and investigate the risk factors for CKD progression in Syrian children.
methodsA single-center observational cohort study was conducted at Children's University Hospital in Damascus, included all patients admitted to the department of pediatric nephrology (inpatient unit) from February 2022 to February 2023, with CKD stages 2-5.
resultsOur study included 100 patients, with a slight female predominance, and mean age of 4.73 years ± 3.7, ranging from 3 months to 14 years. CKD causes were congenital anomalies of the kidney and urinary tract (CAKUT) in 79%, hereditary nephropathies in 12%, and glomerular diseases in 9%. After one year of follow-up, 38% of them were stable on conservative management and 62% had kidney failure. Gender, age, and family history of CKD were not statistically significant factors in CKD progression. The progression rate to kidney failure was highest in glomerular diseases, with 100% for glomerulonephritis and 80% for steroid-resistant nephrotic syndrome, and the progression rate in kidney dysplasia patients was 78.1%. Proteinuria, metabolic acidosis, hyperparathyroidism, hypertension, anemia, and hyperphosphatemia were significantly associated with CKD progression.
conclusionsIn Syrian children, CAKUT are the leading cause of CKD. CKD progression is most rapid in glomerular diseases. Modifiable risk factors, especially hypertension and proteinuria, play a significant role in CKD progression, which highlights the importance of early detection and appropriate management of these factors.
Indexed as
Identifiers
40418281What OpenQuestion holds
Registered trials
Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.