ArticleEJNMMI physics2025
First performance evaluation of easyPET.3D, a high-resolution and cost-effective benchtop preclinical PET scanner.
Article in EJNMMI physics, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Not yet cited in PubMed.
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Abstract
purposeEasyPET.3D is a preclinical positron emission tomography (PET) scanner with a unique scanning method based on two face-to-face detector modules with two axes of motion. Its performance evaluation is presented using the NEMA NU-4 standards and an animal model.
methodsEach detector module consists of a 32 × 2 pixelated cerium-doped lutetium-yttrium oxyorthosilicate (LYSO:Ce) scintillator array with individual crystals of 2.0 × 2.0 × 30 mm
resultsSpatial resolution at the FoV centre (CFoV) in radial, tangential, and axial directions was 0.98±0.08, 0.97±0.06 and 0.94±0.08 mm, respectively. An absolute sensitivity of 0.23% was measured at CFoV. The mouse-like phantom SF was 16% (913 cps at 18 MBq). Recovery coefficients in the IQ phantom varied from 21±34% to 85±50% (1 to 5 mm diameter rods, accordingly). The uniformity was 17.6%, and spill-over ratios for water-filled and air-filled chambers were 0.49 and 0.40, respectively.
conclusionEasyPET.3D geometry favours the reduction of parallax error, despite its low sensitivity. The system linearity is suitable for the low range of activities (7-8 MBq) used for mice imaging. The overall performance showed that easyPET.3D has potential for entry-level preclinical applications.
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