Evidence map›Paper›PMID 40418113›Full record

SynthesisBrain and behavior2025

Accuracy of Machine Learning in Predicting Post-Stroke Depression: A Systematic Review and Meta-Analysis.

Husile Husile, Qinglin Bao, Sarula Sarula, Chu La, Wujisiguleng Wujisiguleng, Siqintu Siqintu, Temuqile Temuqile

Abstract readSystematic ReviewMeta-Analysis
In one paragraph

Synthesis in Brain and behavior, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 4 papers.

0numbers the graph read from it
0cells of the map it votes in
4citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

4 citing papers in PubMed.

  1. Article
  2. Article
  3. Article
  4. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

7 authors.

Husile Husile *Inner Mongolia Medical University, Hohhot Inner Mongolia, China.ORCID https://orcid.org/0009-0009-9512-2417
Qinglin Bao *International Mongolian Hospital of Inner Mongolia, Hohhot Inner Mongolia, China.
Sarula SarulaInternational Mongolian Hospital of Inner Mongolia, Hohhot Inner Mongolia, China.
Chu LaCollege of Traditional Chinese Medicine, Beijing University of Chinese Medicine, Beijing, China.
Wujisiguleng WujisigulengInternational Mongolian Hospital of Inner Mongolia, Hohhot Inner Mongolia, China.
Siqintu SiqintuInner Mongolia Medical University, Hohhot Inner Mongolia, China.
Temuqile TemuqileInternational Mongolian Hospital of Inner Mongolia, Hohhot Inner Mongolia, China.

Funding

No grant is acknowledged in the PubMed record.

6 · The paper itself

Abstract

introductionPost-stroke depression is one of the important complications of stroke and affects patients' quality of life. Early identification of post-stroke depression is crucial for its timely prevention. The accuracy of machine learning as a prediction method is controversial. To systematically analyze these studies, we conducted a systematic evaluation to review the effectiveness of the machine learning prediction models in predicting post-stroke depression based on meta-analysis.

methodsAs of November 20, 2023, we conducted a systematic literature retrieval in databases such as PubMed, Embase, Cochrane, and Web of Science to investigate machine learning model predictions in patients who had post-stroke depression. The tool used in this study to assess the quality of the retrieved literature is PROBAST (Prediction model Risk of Bias Assessment Tool).

resultsA total of 28 studies with 85,223 patients as subjects were included in the meta-analysis. According to data, the c-index in the validation set was significantly lower than that in the training set and may have been at risk of overfitting, even though there was a desirable accuracy. In addition, we found substantial differences in the duration of follow-up for post-stroke depression, and meta-regression showed that the c-index based on the prediction models did not decay with longer follow-up.

conclusionsReasonable prediction models are effective prediction tools for post-stroke depression. A reasonable prediction seems to predict the risk of post-stroke depression occurrence at different time points and can provide a prevention tool specific to the risk.

Indexed as

DepressionMachine LearningStrokeHumanspost‐stroke depressionprediction modelsystematic review

Identifiers

PMID40418113
PMCPMC12105110

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.