Evidence map›Paper›PMID 40417953›Full record

ArticleSmall methods2026

On-Tip Polymerization Method for Multimodal Characterization of Nanoparticles with Electron/Ion Imaging and Atom Probe Tomography.

Aristide Djoulde, Anup Sharma, Alfred Bekoe Appiagyei, Levi Tegg, Yang Liu, Lian Zhang, Julie M Cairney, Yunlong Tang, Jing Fu

Abstract read
PubMed Full text at PMC Publisher
In one paragraph

Article in Small methods, 2026. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 2 papers.

0numbers the graph read from it
0cells of the map it votes in
2citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

2 citing papers in PubMed.

  1. Review
  2. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

9 authors.

Aristide DjouldeDepartment of Mechanical and Aerospace Engineering, Monash University, Clayton, Victoria, 3800, Australia.ORCID https://orcid.org/0000-0002-1944-8919
Anup SharmaDepartment of Mechanical and Aerospace Engineering, Monash University, Clayton, Victoria, 3800, Australia.
Alfred Bekoe AppiagyeiDepartment of Chemical and Biological Engineering, Monash University, Clayton, Victoria, 3800, Australia.
Levi TeggSchool of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, Camperdown, NSW, 2006, Australia.
Yang LiuMonash Centre for Electron Microscopy, Monash University, Melbourne, Victoria, 3800, Australia.
Lian ZhangDepartment of Chemical and Biological Engineering, Monash University, Clayton, Victoria, 3800, Australia.
Julie M CairneySchool of Aerospace, Mechanical and Mechatronic Engineering, University of Sydney, Camperdown, NSW, 2006, Australia.
Yunlong TangDepartment of Mechanical and Aerospace Engineering, Monash University, Clayton, Victoria, 3800, Australia.
Jing FuDepartment of Mechanical and Aerospace Engineering, Monash University, Clayton, Victoria, 3800, Australia.ORCID https://orcid.org/0000-0002-7752-5417

Funding

Australian Research Council LE0882821Australian Research Council LE200100132Australian Research Council LP220100365
6 · The paper itself

Abstract

This work presents a novel method for exploring the structures and chemistry of nanoparticles (NPs), addressing challenges in multimodal and correlative microscopy analysis. The proposed method utilizes a "needle-eye" design, featuring a through-microchannel fabricated at the needle tip. The microchannel and its surface are tuned via focused ion beam (FIB) milling and plasma treatment, enabling NPs dispersed in a resin precursor to be confined in the microchannel due to a pressure gradient upon immersion. The retained suspension is promptly polymerized in situ on the tip and shaped by FIB milling into specific geometries, including but not limited to a micropillar, lamella, and nanoneedle. Here, to demonstrate its applicability, a mixed metal oxide catalyst prepared by the needle-eye approach is characterized with energy-dispersive X-ray spectroscopy (EDX), FIB secondary ion mass spectrometry (FIB-SIMS), (scanning) transmission electron microscopy ((S)TEM), and atom probe tomography (APT). The results validate the ability of the method to achieve multimodal, combining correlative and complementary high-resolution structural and chemical imaging of individuals and clustered NPs. The proposed method confines picoliter-scale samples (6-60 pL) at a tip, eliminating lift-out and microtomy while enabling comprehensive analysis via combined microscopy techniques.

Indexed as

mixed metal oxide catalystmultimodal and correlative microscopynanoparticlesneedle‐eye designon‐tip polymerization

Identifiers

PMID40417953
PMCPMC12825343

What OpenQuestion holds

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Registered trials

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Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.