Evidence map›Paper›PMID 40417862›Full record

ArticleAdvanced healthcare materials2025

Kirigami-Inspired Breathable Smart Contact Lens for Wireless Monitoring of Corneal Hypoxia and Microenvironment.

Jiaxue Zhu, Ling Yang, Qing Yang, Yin Huang, Yuhang Li, Yueqing He, Xuxu Yang, Zhiyan Yang, Yonghong Jiao, Wenbin Wei and 2 more

Abstract read
In one paragraph

Article in Advanced healthcare materials, 2025. The graph could read no effect estimate from its abstract, so it casts no vote on the map. Cited by 5 papers.

0numbers the graph read from it
0cells of the map it votes in
5citing papers in PubMed
–field-weighted citation impact
1 · What the graph read from it

What it found

Each row is one number read from the abstract, on the scale the paper reported it, with its interval. Left of the dashed line favours the treatment, right favours the comparator. Under each row is the sentence it came from. New to these charts? A ten-minute tutorial.

The abstract states no effect estimate the extractor could read, or names no intervention and outcome on the map, so this paper lights no cell and moves no belief. It is still indexed, cited and linked below.

2 · The registry

The trial behind it

Trials whose registry record cites this paper, or whose number appears in the abstract. A trial that started after this paper was published is citing it as background, not reporting it.

Neither the registry nor the abstract names a trial number. If this is a trial report, that itself is worth knowing.

3 · Its place in the literature

Who cites it

5 citing papers in PubMed.

  1. Review
  2. Article
  3. Smart contact lenses: recent advances and future challenges in eye disease diagnosis and treatment.Graefe's archive for clinical and experimental ophthalmology = Albrecht von Graefes Archiv fur klinische und experimentelle Ophthalmologie · 2026
    Review
  4. Article
  5. Article
4 · The record

Corrections and comments

PubMed lists nothing against this paper. Absence here is not a guarantee, only a check that was made.

5 · Who and what money

Authors and funding

12 authors.

Jiaxue ZhuLaboratory of Flexible Electronics Technology, Tsinghua University, Beijing, 100084, China.
Ling YangLaboratory of Flexible Electronics Technology, Tsinghua University, Beijing, 100084, China.
Qing YangLaboratory of Flexible Electronics Technology, Tsinghua University, Beijing, 100084, China.
Yin HuangKey Laboratory of Advanced Technologies of Materials, Ministry of Education, School of Materials Science and Engineering, Southwest Jiaotong University, Chengdu, 610031, China.
Yuhang LiInstitute of Solid Mechanics, Beihang University (BUAA), Beijing, 100191, China.
Yueqing HeBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Xuxu YangDepartment of Engineering Mechanics, Zhejiang University, Hangzhou, Zhejiang, 310027, China.
Zhiyan YangLaboratory of Flexible Electronics Technology, Tsinghua University, Beijing, 100084, China.
Yonghong JiaoBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Wenbin WeiBeijing Tongren Eye Center, Beijing Tongren Hospital, Capital Medical University, Beijing, 100730, China.
Yihao ChenLaboratory of Flexible Electronics Technology, Tsinghua University, Beijing, 100084, China.
Xue FengLaboratory of Flexible Electronics Technology, Tsinghua University, Beijing, 100084, China.ORCID 0000-0001-9242-8474

Funding

China Postdoctoral Science Foundation 2023M741893National Natural Science Foundation of China 11921002National Natural Science Foundation of China 12272022National Natural Science Foundation of China U20A6001Tsinghua Precision Medicine Foundation 100010104
6 · The paper itself

Abstract

Severe corneal dysfunctions caused by corneal hypoxia and microenvironmental imbalance threaten hundreds of millions of people's eye health, leading to neovascularization, keratitis, and even vision loss, particularly among contact lens wearers. However, there are no accessible digital tools for wearable and continuous monitoring of corneal oxygen and microenvironment status. Here, a kirigami-inspired breathable smart contact lens for wireless monitoring of corneal hypoxia and microenvironment is presented. The ultrathin (55 µm) and flexible sensing device enables digitalized, in situ and precise monitoring of key eye health indicators: dissolved oxygen, humidity, and temperature (R

Indexed as

Contact LensesCorneaHypoxiaWireless TechnologyAnimalsDogsHumansHydrogelsMonitoring, PhysiologicOxygenWearable Electronic DevicesHydrogelsOxygenbreathable smart contact lenscorneal hypoxiakirigami‐inspired circuitryocular surface microenvironmentwireless multiparameter monitoring

Identifiers

PMID40417862
PMCPMC12264840

What OpenQuestion holds

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LicenceCC BY-NC
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Registered trials

None linked

Read under generation 80e0d062 · epoch 390. Bibliography from PubMed, PubMed Central and OpenAlex; grants from NIH RePORTER; trial links from ClinicalTrials.gov; estimates, votes and beliefs from the OpenQuestion graph.